摘要
干扰素是一类具有调控免疫和抗病毒功能的多功能细胞因子,在全身性疾病中的作用显著,在中枢神经系统中发挥抗病毒及免疫调节等作用,但其可能通过影响炎症与免疫蛋白沉积等导致帕金森病(PD)的发病。近年来,越来越多的研究关注于干扰素对PD发病机制及症状的影响。本文主要就干扰素对PD发病机制及症状的影响进行综述。
Interferons are a group of multifunctional cytokines with immune and antiviral functions.They play important roles in systemic diseases,central nervous system antiviral and immunomodulatory roles.However,it may contribute to the pathogenesis of Parkinson s disease(PD)by affecting inflammation and immune protein deposition.In recent years,more and more studies have focused on the effect of interferon on the pathogenesis and symptoms of PD.This article reviewed the effects of interferon on the pathogenesis and symptoms of PD.
作者
朱彤
曾广红
周杰
ZHU Tong;ZENG Guanghong;ZHOU Jie(Department of Neurosurgery,The Second Clinical College of Lanzhou University,Lanzhou 730030,China;不详)
出处
《临床神经外科杂志》
2024年第1期99-101,共3页
Journal of Clinical Neurosurgery
基金
甘肃省卫生行业科研计划项目(GSWSKY2018-43)
联勤保障部队第九四〇医院研究生课题项目(2022yxky011)。
关键词
帕金森病
干扰素
神经系统
parkinson s disease
interferon
nervous system