以异常阴道出血为首发症状的肺腺癌子宫内膜转移一例并文献复习

Endometrial Metastasis of Lung Adenocarcinoma with Abnormal Vaginal Bleeding as the First Symptom:A Case Report and Literature Review

原发性支气管肺癌简称肺癌,是世界各国发病率和死亡率较高的恶性肿瘤之一。近年来,女性肺癌发病率升高且多为肺腺癌。因肺癌早期症状隐匿,发现时常伴有转移。报道1例肺腺癌子宫内膜转移病例,该患者因异常阴道出血就诊,诊刮术后病理提示腺癌。结合免疫组织化学检查和影像学检查,排除其他部位肿瘤来源可能后,确诊为肺腺癌转移至子宫内膜。肺癌转移至子宫内膜极其罕见,极可能被漏诊、误诊。回顾性分析该病例资料并复习相关文献,以期提高临床对肺腺癌子宫内膜转移的警惕。

Primary bronchial lung cancer,commonly known as lung cancer,is one of the malignant tumors with high morbidity and mortality in the world.In recent years,the incidence of lung cancer in women has increased,and most of them are lung adenocarcinoma.Because the early symptoms of lung cancer are occult,it is often detected when metastasis has already occurred.We report a case of endometrial metastasis of lung adenocarcinoma.The patient presented with abnormal vaginal bleeding,and the pathology after curettage indicated adenocarcinoma.After immunohistochemical examination and imaging examination were combined to exclude the possibility of tumor origin in other sites,the diagnosis was confirmed as lung adenocarcinoma metastasis to the endometrium.Metastasis of lung cancer to the endometrium is extremely rare and is likely to be missed or misdiagnosed.In this paper,the data of a case of endometrial metastasis of lung adenocarcinoma were retrospectively analyzed and the relevant literatures were reviewed in order to enhance the clinical vigilance of endometrial metastasis of lung adenocarcinoma.