槐轩医学用药规律分析与扶阳思想探讨

Analysis of Medication Rules of Huaixuan Medical School and Discussion on Ideas of Reinforcing Yang

目的:通过挖掘、研究《槐轩医学全书》中的药物应用规律,提炼分析槐轩医学临床思想,与扶阳医派一脉理论比较,探究古今扶阳思想之差异。方法:对《槐轩医学全书》中所涉方剂与药物进行梳理提取,对符合纳入标准的药物进行统计并建立数据库,运用SPSS Statistics24.0和SPSS Modeler18.0具体分析其用药频次、性味归经、用药剂量以及关联规则、聚类。结果:共筛选方剂386首,涉药327味,用药以性温、味辛甘为主,归经多为脾经,性味归经分析呈现较强的集中现象。关联分析以中焦脾胃药物应用搭配为核心,形成具辛甘化阳理法的15个药对;聚类组成6个新方;在姜桂附应用剂量统计上,发现其趋向审慎。结论:槐轩医学以温补为特色,重视后天资先天,注重脾胃枢机调理,不偏颇阴阳,形成一系列特色理法,对扶阳学派影响深远,但与后世扶阳学派理论又有很大不同。

Objective:To explore the differences between ancient and modern ideas of reinforcing yang by exploring and studying the medication rules in Huai Xuan Yi Xue Quan Shu(Huaixuan Medical Encyclopedia),extracting and analyzing the clinical ideas of Huaixuan Medical School,and by comparing with the theories of Yang-Reinforcing Medical School.Methods:The prescriptions and medicinals involved in Huai Xuan Yi Xue Quan Shu were sorted out and extracted,and the medicinals meeting the inclusion criteria were statistically analyzed and a database was established.SPSS Statistics 24.0 and SPSS Modeler 18.0 were used to specifically analyze the medicinal frequency,natures,flavors,channel entry,medication dosage,association rules and clustering.Results:A total of 386 prescriptions were screened,involving 327 kinds of medicinals.The medicinals used were mainly warm in nature and sweet in flavor,and mainly entered the spleen channel,which showed strong concentration.The correlation analysis showed that the key was based on the combination of medicinals for the spleen and the stomach of the middle energizer,and 15 medicinal pairs were formed;clustering analysis showed that there were 6 new prescriptions;and it was found that the dose of Zingiberis Rhizoma,Cinnamomi Cortex and Aconiti Lateralis Radix Praeparata tended to be cautiously decided according to medication dosage analysis.Conclusion:Huaixuan Medical School is characterized by warming and supplementing,who attaches importance to supplementing and boosting both the postnatal and the prenatal spleen and stomach.It also focuses on regulating the pivot movement of the spleen and the stomach and harmonizing yin and yang.It has formed a series of characteristic theories and methods,which have a profound influence on Yang-Reinforcing Medical School,but they also have great differences from them.