探讨产前及输血前检测孕产妇ABO与RhD血型的临床意义

To explore the clinical significance of detecting ABO and RhD blood group in pregnant women before and after transfusion

目的探讨产前及输血前检测孕产妇ABO与RhD血型的临床意义。方法选取80例进行体检的孕产妇,所有孕产妇均进行血型鉴定,并完成不规则抗体检测,观察其检验结果。结果80例孕产妇中,不规则抗体阳性有12例(15.00%),包括有妊娠史的孕产妇8例和输血史的孕产妇4例。12例不规则抗体阳性结果的孕产妇中A型血有3例(25.00%),B型血有3例(25.00%),O型血有5例(41.67%),AB型血有1例(8.33%)。其中,RhD阳性占11/12(91.67%),抗E占比最高,为5/12(41.67%),抗Ec占2/12(16.67%),抗D占2/12(16.67%),抗C占1/12(8.33%),抗c占1/12(8.33%)。结论在产前和输血前为孕产妇实施不规则抗体、ABO和RhO血型检测,可为临床上明确母婴血型的不匹配和易流产情况或新生儿溶血病等提供依据,以尽早加以筛查和处理,具有重要的检验指导性意义。

Objective To explore the clinical significance of detecting ABO and RhD blood group in pregnant women before and after transfusion.Methods 80 pregnant women were selected for physical examination.Blood type identification was performed for all of them,and irregular antibody detection was performed to observe the test results.Results Among the 80 pregnant women,12(15.00%)were irregular antibody positive,including 8 pregnant women with pregnancy history and 4 pregnant women with blood transfusion history.Among the 12 pregnant women with irregular antibody positive results,there were 3 cases of type A blood(25.00%),3 cases of type B blood(25.00%),5 cases of type 0 blood(41.67%)and 1 case of type AB blood(8.33%).Among them,RhD positive accounted for 11/12(91.67%),anti-E accounted for the highest proportion,5/12(41.67%),anti-EC accounted for 2/12(16.67%),anti-D accounted for 2/12(16.67%),anti-C accounted for 1/12(8.33%),anti-C accounted for 1/12(8.33%).Conclusion The implementation of irregular antibody,ABO and Rho blood type detection for pregnant women before and after transfusion can provide a basis for clinically identifying the mismatch of maternal and infant blood type and the situation of easy abortion or neonatal hemolytic disease,so as to screen and treat as early as possible,which has important test guiding significance.