老年淋巴瘤患者自我感受负担及生命质量现况及其相关性研究

Current Status and Correlation of Self-perceived Burden and Quality of Life in Elderly Patients with Lymphoma

目的 分析老年淋巴瘤患者的自我感受负担(self-perceived burden,SPB)、生命质量及其相关性。方法 经便利抽样法选取2019年3月—2022年3月间四川大学华西医院血液内科收治的505例老年淋巴瘤患者作为研究对象,采用一般资料调查表、自我感受负担量表(SPBS)和淋巴瘤患者生命质量测定量表(FACT-Lym)对患者进行调查,评估患者SPBS和FACT-Lym评分,并分析两者之间相关性。结果 老年淋巴瘤患者SPBS总分为(31.76±1.59)分,SPB分级中,无61例,轻度167例,中度147例,重度130例;FACT-Lym评分中,情感维度(10.98±2.45)分,生理(13.02±2.83)分,社会家庭(13.01±2.65)分,功能(11.97±3.42)分,淋巴瘤附加关注(28.95±1.81)分,FACT-Lym总分为(77.93±7.52)分;随着SPB严重程度升高,FACT-Lym各维度评分依次降低,不同组别间比较差异具有统计学意义(P<0.05);Pearson相关性分析和多重线性回归分析显示,老年淋巴瘤患者SPBS各维度评分与FACT-Lym各维度评分呈显著负相关(P<0.05)。结论 老年淋巴瘤患者存在不同程度自我感受负担心理,且SPB越严重,生命质量越差,建议采取相应措施干预,以提升其生命质量。

Objective To analyze the self-perceived burden(SPB),quality of life and their correlation in elderly patients with lymphoma.Methods 505 elderly patients with lymphoma who were treated in the department of hematology of West China Hospital,Sichuan University from March 2019 to March 2022 were selected as the research subjects by convenient sampling.General information questionnaire,Self-Perceived Burden Scale(SPBS)and Functional Assessment of Cancer Therapy-Lymphoma(FACT-Lym)were used to investigate the patients.The SPBS scores and FACT-Lym scores of patients were evaluated and the correlation between them was analyzed.Results The total SPBS score of elderly patients with lymphoma was(31.76±1.59)points,and SPB grading showed there were 61 cases of no SPB,167 cases of mild SPB,147 cases of moderate SPB and 130 cases of severe SPB.The scores of dimensions of emotion,physiology,social family,function and lymphoma additional concern and total score of FACT-Lym were(10.98±2.45)points,(13.02±2.83)points,(13.01±2.65)points,(11.97±3.42)points,(28.95±1.81)points and(77.93±7.52)points.As the severity of SPB increased,the scores of all dimensions of FACT-Lym decreased in turn,and there were statistical differences among different groups(P<0.05).Pearson correlation analysis and multiple linear regression analysis showed that the scores of dimensions of SPBS were negatively correlated with the scores of dimensions of FACT-Lym in elderly patients with lymphoma(P<0.05).Conclusion Elderly patients with lymphoma have different degrees of self-perceived burden,and the more serious the SPB,the worse the quality of life.It is suggested to take corresponding measures to improve the prognosis and quality of life.