高效液相色谱——串联质谱法在蜂王浆高风险药物残留检测中的应用

Application of high performance liquid chromatography-tandem mass spectrometry in royal jelly high-risk drug residue detection

蜂王浆作为一种天然保健品,备受国内外消费者青睐。随着国内外标准对蜂王浆中高风险药物残留限量要求的提高,对其检测技术的要求也越来越高。高效液相色谱--串联质谱(HPLC-MS/MS)以其快速、高灵敏度、高选择性等优点被广泛应用于蜂王浆高风险药物残留检测,在蜂王浆复杂基质中的痕量成分检测中发挥了独特的技术优势。本文综述了近十多年来HPLC-MS/MS在蜂王浆高风险残留检测中的应用和进展,并对其应用潜力和未来发展前景进行展望,以期为HPLC-MS/MS技术在蜂王浆高风险药物残留检测领域更好地推广应用提供参考。

As a kind of natural green health product,royal jelly is favored by consumers at home and abroad.Along with the domestic and foreign standard to the high-risk drug residue limit request enhancement in the royal jelly,the demand for its detection technology is also getting higher and higher.High performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS),with its advantages of rapidity,high sensitivity,high selectivity,is widely used in royal jelly high-risk drug residue detection.This technology has played a unique technical advantage in the detection of trace components in complex matrix of royal jelly.This paper reviewed the application and progress of HPLC-MS/MS in royal jelly high-risk drug residue detection,and prospected its future application potential and development prospects,so as to provide reference for the promotion and application of HPLC-MS/MS technology in the field of royal jelly high-risk drug residue detection.