摘要
目的建立氨基己酸注射液的药物利用评价(DUE)标准,评价和分析氨基己酸注射液的临床应用情况。方法以氨基己酸注射液说明书为基础,参考相关文献,建立氨基己酸注射液DUE标准细则,包括用药指征、用药过程、用药结果等项目。采用回顾性研究方法,对福建中医药大学附属福鼎市医院2021年7月—2022年6月使用过氨基己酸注射液的住院患者用药进行合理性评价。结果共纳入143份病历,其中临床应用完全符合评价标准的有73例,不完全符合的有70例,不合理率为48.95%。氨基己酸注射液临床应用常见的不合理问题为围手术期预防用药给药时机不适宜(26.57%)、围手术期预防用药超疗程(23.08%)和存在禁忌证(7.69%)。结论建立的氨基己酸注射液DUE标准科学、实用,经评价该院氨基己酸注射液的使用不合理率较高,需加强氨基己酸注射液合理用药的管理。
Objective To establish drug use evaluation(DUE)criteria for aminocaproic acid injection,and to evaluate and analyse clinical use of aminocaproic acid injection.Methods Based on the aminocaproic acid injection drug label,DUE of aminocaproic acid injection from three aspects(indications,medications and medication results)were established with reference to relevant literature.A retrospective survey was conducted to evaluate the rationality of medication for inpatients who used aminocaproic acid injection from July 1,2021 to June 30,2022 in Fuding Hospital of Fujian University of Traditional Chinese Medicine.Results A total of 143 midical records were included.73 cases fully met the DUE criteria,70 cases did not fully meet the DUE criteria,and the unreasonable rate was 48.95%.The most common types of irrational using of aminocaproic acid injection were inappropriate timing of perioperative prevention of medication(26.57%),overcourse in perioperative prevention of medication(23.08%),and contraindications(7.69%).Conclusions The aminocaproic acid injection DUE standard established is scientific,practical,the irrational rate of aminocaproic acid injection use is relatively high in this hospital,and the management of rational use of aminocaproic acid injection needs to be strengthened.
作者
魏爱珍
王美章
章靓
张先波
张进华
Ai-Zhen WEI;Mei-Zhang WANG;Liang ZHANG;Xian-Bo ZHANG;Jin-Hua ZHANG(Department of Pharmacy,Fuding Hospital of Fujian University of Traditional Chinese Medicine,Fuding 355200,Fujian Province,China;Department of Pharmacy,People Affiliated Hospital of Fujian University of Traditional Chinese Medicine,Fuzhou 350004,China;Department of Pharmacy,Fujian Maternal and Child Health Hospital,Fuzhou 350001,China)
出处
《药物流行病学杂志》
CAS
2023年第12期1331-1337,共7页
Chinese Journal of Pharmacoepidemiology
关键词
氨基己酸注射液
药物利用评价
病历点评
合理用药
Aminocaproic acid injection
Drug use evaluation
Medical record evaluation
Rational drug use