上海市临床检验中心复合过敏原计划室间质量评价结果分析

Analysis of external quality assessment results for compound allergen program performed by Shanghai Center for Clinical Laboratory

目的通过开展室间质量评价(简称室间质评),评价复合过敏原计划各项目检测结果的一致性。方法收集2022年至2023年参加上海市临床检验中心复合过敏原计划(包括屋尘螨、粉尘螨、猫毛、艾蒿、梯牧草、牛奶、榛子、花生项目)的室间质评回报数据,对8个项目的回报结果进行统计分析。结果复合过敏原计划共开展4次,参加实验室数分别为104、107、124和122家,总体合格率分别为99.04%、99.07%、99.19%和100%。屋尘螨、粉尘螨、艾蒿项目各组的指定值均相同,各试剂组结果一致性较高;猫毛及牛奶项目试剂组间出现指定值阴、阳性不一致情况;梯牧草、榛子及花生项目除复合靶点试剂无法检出外,其余各组试剂结果一致性较高。结论复合过敏原计划参加实验室数量逐步增加,涵盖的8个项目的室间质评结果良好,总体合格率均较高,各试剂厂家一致性较好。

Objective To evaluate the consistency of testing results for various items in the compound allergen program by conducting external quality assessment scheme.Methods The feedback results of external quality assessment for the compound allergen program performed by Shanghai Center for Clinical Laboratory(SCCL)during 2022 and 2023,including house dust mite,dust mite,cat hair,mugwort,terraced grass,milk,hazelnut,and peanut,were collected and analyzed.Results The compound allergen program was conducted four times,with 104,107,124,and 122 participating laboratories,and the qualification rates were 99.04%,99.07%,99.19%,and 100%,respectively.The specified values of the house dust mite,dust mite,and mugwort items were the same in each group,and the consistency of the results for different reagent groups was relatively high.There was inconsistency in the specified values(negative or positive)of cat hair and milk items between different reagent groups.The consistency of the results among the other reagent groups was high,except for the reagent used for detecting compound targets by which the terraced grass,hazelnut,and peanut allergens could not be detected.Conclusion The number of participating laboratories in the compound allergen program is gradually increasing,and the external quality assessment results of the 8 items covered are good.The overall qualification rate is high,and the consistency of reagents from different manufacturers is good.