癫痫患儿的智力结构、个性与行为特征研究

Analysis of intelligence profile,personality and behaviour of children with primary generalized epilepsy

目的探讨原发性全身强直和 /或阵挛发作 (GTCS)癫痫患儿的智力、个性和行为特征。方法采用中国修订版的儿童韦氏智力量表、艾森克个性问卷调查、Achenbach儿童行为筛查量表对 3 5例癫痫患儿进行心理学测试 ,并与健康儿童测试结果进行对比分析。结果癫痫患儿言语商、操作商和总智商明显低于对照组 (P <0 0 1) ,操作量表中填图亚项未见异常 ,其余亚项以及言语量表各项得分均明显低下 (P <0 0 1) ,提示注意力、记忆力、心算、概括、判断、眼手协调、想象力、解决问题能力等普遍受累。癫痫组总智商正常 17例 (4 8 5 7% ) ,边缘水平 13例 (3 7 14 % ) ,轻度智力低下 5例 (14 2 9% )。对照组总智商全部正常。癫痫组行为异常率高达 3 8 71% ,而对照组仅为 6 45 % ,主要行为问题包括攻击性、多动、社交退缩、分裂症样和抑郁。个性测试两组无明显差异。结论原发性全身强直和 /或阵挛发作癫痫患儿存在明显的认知损伤和行为异常。

ObjectiveTo evaluate the intelligence profile,personality and behaviour disorders of children with primary generalized tonic and/or clonic seizures.MethodsUsing Chinese modification of Wechsler Intelligence Scale for Children,Eysenk Personality Questionnaire(EPQ),and Achenbach Child Behaviour Check List,neuropsychological assessment of 35 cases aged 6-14 years and the normals with the similar age and sex were makenand compared.ResultsExcept picture completion ,all the subtests scales of children with epilepsy were significantly lower than those of the controls (P<0.01). A significant difference of average FIQ( P<0.001) was observed between experimental group (85.86) and control group (103.60).There were 13 cases(37.14%) in experimental group whose FIQ were in broderline range, FIQ of 5 cases(14.29%) was in lower range,while none abnormal in the controls.The children with epilepsy had more abnormal behaviours than that of the controls(abnormal rates were 38.71% and 6.45% respectively).Statistical analysis showed no difference of EPQ scales between the two groups.Conclusions Children with primary generalized epilepsy maybe complicate with cognitive deficit and behaviour disorder.