摘要
Liquid-liquid phase separation(LLPS)emerges as a general approach for the generation of biomolecular condensates,which play important roles in various biological processes,including chromatin organization,transcription,translation,protein degradation,and signal transduction^([1]).Irregular phase separation is often associated with cancer,neurodegeneration,and other human diseases^([2]).
作者
田超
万圣鹏
卢毅
王平
葛欣
方兰
Chao Tian;Shengpeng Wan;Yi Lu;Ping Wang;Xin Ge;Lan Fang(Cancer Center,Shanghai Tenth People’s Hospital,Tongji University School of Medicine,Tongji University,Shanghai 200072,China;Science Center of Nanocatalytic Medicine,Tongji University School of Medicine,Tongji University,Shanghai 200331,China)
基金
supported by the National Key Research and Development Program of China(2022YFC3401500,2020YFA0803201,and 2021YFA1302200)
the National Natural Science Foundation of China(31830053,31920103007,82341028,82122056,82073153,81972676,31900568,and 32270745)
the Natural Science Foundation of Shanghai(23ZR1466500)
the Shanghai Municipal Health Commission(2022YQ067)
the Fundamental Research Funds for the Central Universities(PA2023000691,PA2023000718,and PA2023000692).
