纳米生物传感器在食源性致病菌检测中的应用研究进展

Recent Progress on the Application of Nano-Biosensors for the Detection of Foodborne Pathogenic Bacteria

食源性致病菌污染对人们的健康造成了极大的威胁,传统检测方法操作繁琐且不能实时检测,因此,构建一种灵敏、安全、简便且消耗少的食源性致病菌检测方法很有探索意义。与传统方法相比,基于纳米生物传感器的检测技术具有特异灵敏、简易快速、检测实时、材料消耗少和检测限低等优势,本文主要阐述了基于纳米生物传感器的方法,并展开讨论了其中单模式、双模式及多模式检测的原理及应用优势,同时对纳米生物传感器在食源性致病菌检测中的应用前景提出展望,以期为优化食源性致病菌的检测方法提供一定参考。

The contamination of foodborne pathogenic bacteria poses great threats to human health.Conventional foodborne pathogen detection methods suffer from the shortcomings of time-consuming,cumbersome,and non-real time.Hence,it is of great significance to explore a sensitive,safe,simple and economical method for foodborne pathogen detection.Compared with the traditional methods,nano-biosensor-based detection assays possess merits such as exceptional sensitivity,high selectivity,real-time detection,low consumption and low limit of detection.In this article,these nano-biosensor-based methods are summarized,and the principles and advantages of single-,dual-and multi-mode detection are comprehensively discussed.Meanwhile,an outlook on the application of nano-biosensors for the detection of foodborne pathogens is given with the goal of providing a reference for the optimization of the existing detection methods for foodborne pathogenic bacteria.