3D-ASL技术在高级别脑胶质瘤术后复发的价值研究

The Value of 3D-ASL Technology in Postoperative Recurrence of High-grade Glioma

目的探讨三维动脉自旋标记灌注成像(3D-ASL)在高级别脑胶质瘤术后肿瘤复发的应用价值。方法回顾性分析2019年12月—2021年12月河北省涿州市医院经穿刺活检或手术病理证实的31例高级别脑胶质瘤术后复发患者作为研究对象。全部患者行磁共振平扫、增强扫描、3D-ASL检查,测量高级别脑胶质瘤术后复发区域、对侧正常脑组织脑血流量(CBF),分为复发组CBF、正常组CBF,进行统计学分析。通过常规磁共振检查阅片与常规磁共振检查联合3D-ASL阅片分别诊断,分析诊断符合率进行统计学比较。结果高级别脑胶质瘤术后复发组CBF明显高于正常组CBF,差异有统计学意义(P<0.05);常规磁共振检查联合3D-ASL阅片诊断高级别脑胶质瘤术后复发的诊断符合率较常规磁共振检查阅片显著提高,差异有统计学意义(P<0.05)。结论3D-ASL技术在高级别脑胶质瘤术后复发中有较高的诊断效能,具有重要的临床应用价值。

Objective To explore the application value of three-dimensional arterial spin labeled perfusion imaging(3D-ASL)in postoperative tumor recurrence of high-grade gliomas(HHG).Methods Retrospective analysis of 31 patients with postoperative recurrence of advanced glioblastoma in our hospital from December 2019 to December 2021.All patients underwent magnetic resonance plain scan,enhanced scan,and 3D-ASL examination to measure the recurrence area of highgrade gliomas after surgery,as well as the cerebral blood flow(CBF)of contralateral normal brain tissue,for statistical analysis.Diagnosis was made by combining conventional magnetic resonance imaging and conventional magnetic resonance imaging with 3D-ASL imaging,and the diagnostic accuracy was analyzed for statistical comparison.Results The CBF in the postoperative recurrence group of high-grade gliomas was signifi cantly higher than that in the normal group,with a signifi cant statistical diff erence(P<0.05).The diagnostic accuracy of conventional magnetic resonance imaging combined with 3D-ASL fi lm reading in diagnosing postoperative recurrence of high-grade gliomas was signifi cantly improved compared to conventional magnetic resonance imaging,and there was a significant statistical difference between the two(P<0.05).Conclusion 3D-ASL technology has high diagnostic efficacy in postoperative recurrence of high-grade gliomas and has important clinical application value.