乙型肝炎患者血清免疫球蛋白水平临床检验结果分析

Analysis of Clinical Test Results of Serum Immunoglobulin Level in Hepatitis B Patients

目的分析乙型肝炎患者血清免疫球蛋白水平临床检验结果。方法选取2019年1月—2023年1月泰安市中医医院接诊的500例乙型肝炎患者作为观察组,依据是否发生肝硬化继续分为肝硬化组(265例)和非肝硬化组(235例);依据肝硬化发展阶段,对肝硬化组继续进行分组,将140例肝硬化代偿期患者分为代偿期组,125例肝硬化失代偿期患者分为失代偿期组;另外,选择同时期300例健康体检人员作为对照组,分析不同分组的免疫球蛋白检测水平。结果观察组与对照组比较,观察组IgG、IgA、IgM水平均明显较高,差异有统计学意义(P<0.05);肝硬化组与非肝硬化组比较,肝硬化组IgG、IgA、IgM水平均明显较高,差异有统计学意义(P<0.05);代偿期组与失代偿期组比较,失代偿期组IgG、IgA、IgM水平均明显较高,差异有统计学意义(P<0.05)。结论临床上根据血清免疫球蛋白检测结果,便于分析乙型肝炎患者的实际病变情况,从而判断肝脏细胞受损情况,为疾病诊疗提供参考依据,值得采纳。

Objective To analyze the clinical results of serum immunoglobulin level in hepatitis B patients.Methods 500 patients with hepatitis B admitted to Tai'an Hospital of Traditional Chinese Medicine from January 2019 to January 2023 were selected as the observation group and divided into 265 patients with cirrhosis and 235 patients without cirrhosis according to whether cirrhosis occurred.Cirrhosis was divided into groups according to the development stage of cirrhosis.Among the cirrhosis group,140 patients were in the compensatory stage.125 cases were decompensated,and 300 healthy persons(control group)were selected during the same period to analyze the immunoglobulin detection levels in different groups.Results Compared with the control group,the levels of IgG,IgA and IgM in the observation group were signifi cantly higher(P<0.05).The levels of IgG,IgA and IgM in liver cirrhosis were signifi cantly higher than those in non-liver cirrhosis(P<0.05).Compared with the decompensated stage,the levels of IgG,IgA and IgM in the decompensated stage were signifi cantly higher(P<0.05).Conclusion The results of serum immunoglobulin detection can be used to analyze the actual lesions of hepatitis B patients,so as to judge the damage of liver cells,and provide reference for the diagnosis and treatment of the disease.