超脉冲CO_(2)点阵激光配合果酸应用于痤疮瘢痕患者中的疗效及对其ECCA评分的改善

Effect of Super Pulse CO_(2) Fractional Laser Combined with Acid on Acne Scar Patients and Improvement of ECCA Score

目的:探讨超脉冲CO_(2)点阵激光配合果酸应用于痤疮瘢痕患者中的疗效及对痤疮瘢痕权重评分(Echelle d’evaluation clinique des cicatrices d’acne,ECCA)的改善情况。方法:选取2021年6月—2022年6月国药葛洲坝中心医院接收的痤疮瘢痕患者86例,按随机数字表法分为两组,对照组43例予以超脉冲CO_(2)点阵激光治疗,观察组43例予以超脉冲CO_(2)点阵激光配合果酸治疗,对比两组的临床疗效、五级整体改善量表(global aesthetic improvement scale,GAIS)评分、ECCA评分、患者满意度及不良反应发生情况。结果:观察组总有效率为95.35%,高于对照组的81.40%,差异有统计学意义(P<0.05);观察组治疗后的GAIS与ECCA评分均优于对照组,差异均有统计学意义(P<0.05);观察组患者满意度为95.35%,高于对照组的78.07%,差异有统计学意义(P<0.05);观察组不良反应发生率为9.30%,与对照组的6.98%比较,差异无统计学意义(P>0.05)。结论:超脉冲CO_(2)点阵激光配合果酸应用于痤疮瘢痕患者治疗中可进一步提升效果,并有效改善ECCA评分,提高患者满意度,且安全性理想。

Objective:To investigate the effect of super pulse CO_(2) fractional laser combined with acid on acne scar patients and the improvement of Echelle d'evaluation clinique des cicatrices d'acne(ECCA).Method:A total of 86 patients with acne scars admitted to Guo Yao Gezhouba Central Hospital from June 2021 to June 2022 were selected,divide into two groups according to the random number table method,43 cases in the control group were treated with super pulse CO_(2) fractional laser,and 43 cases in the observation group were treated with super pulse CO_(2) fractional laser combined with acid,the clinical efficacy,global aesthetic improvement scale(GAIS)score,ECCA score,patient satisfaction and adverse reactions of the two groups were compared.Result:The total effective rate of observation group was 95.35%,higher than 81.40%of control group,the difference was statistically significant(P<0.05).GAIS and ECCA scores of observation group were better than those of control group after treatment,the differences were statistically significant(P<0.05).The satisfaction of patients in observation group was 95.35%,higher than 78.07%in control group,the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 9.30%,compared with 6.98%in the control group,the difference was not statistically significant(P>0.05).Conclusion:Super pulse CO_(2) fractional laser combined with acid in the treatment of acne scar patients can further improve the efficacy,effectively improve the ECCA score,as well as improve patient satisfaction,and have ideal safety.