慢性前列腺炎患者继发性功能障碍的临床特征分析

Clinical characteristics of secondary dysfunction in patients with chronic prostatitis

目的探讨慢性前列腺炎患者继发性功能障碍的临床特征及其影响因素。方法选取2019年1月至2022年12月儋州市人民医院收治的497例慢性前列腺炎患者作为研究对象。根据是否继发性功能障碍分为观察组(n=202)和对照组(n=295),比较两组的临床资料,分析慢性前列腺炎患者继发性功能障碍的临床特征及相关影响因素。结果两组体重指数(BMI)、吸烟史、婚姻状况、临床分型、前列腺压痛/钙化、前列腺液检测、性激素水平比较,差异无统计学意义(P>0.05);两组年龄、无节制性生活、病程、饮酒史及盆底肌肉紧张占比比较,差异具有统计学意义(P<0.05);观察组慢性前列腺炎症状评分(NIH-CPSI)、国际勃起功能指数问卷表-5(IIEF-5)评分显著高于对照组,合并有焦虑、抑郁占比更高,中国早泄患者性功能评分表-5(CIPE-5)评分显著低于对照组,差异具有统计学意义(P<0.05)。Logistic回归分析显示,年龄、病程、病情严重程度、饮酒史、前列腺液白细胞计数(>10/HP)、盆底肌肉紧张、抑郁、焦虑是慢性前列腺炎继发性功能障碍的影响因素(P<0.05),且NHI-CPSI评分高、长病程、盆底肌肉紧张及焦虑是慢性前列腺炎继发性功能障碍的独立危险因素(P<0.05)。结论慢性前列腺炎继发性功能障碍患者多有年龄大、病程长、病情较严重、喜饮酒的特点,且症状严重程度、盆底肌肉紧张度、精神焦虑是慢性前列腺炎继发性功能障碍的独立危险因素。

Objective To explore the clinical characteristics of secondary dysfunction in patients with chronic prostatitis and its influencing factors.Methods A total of 497 chronic prostatitis patients admitted to Danzhou People′s Hospital from January 2019 to December 2022 were selected as study subjects.They were divided into observation group(n=202)and control group(n=295)according to whether they had secondary dysfunction.The clinical data of the two groups were compared to analyze the clinical characteristics of secondary dysfunction in patients with chronic prostatitis and the related influencing factors.Results There were no statistically significant differences in body mass index(BMI),smoking history,marital status,clinical classification,prostatic tenderness/calcification,prostatic fluid test,and sex hormone levels between the two groups(P>0.05).There were statistically significant difference in age,uncontrolled sex life,disease course,history of alcohol consumption,and pelvic floor muscle tension between the two groups(P<0.05).The scores of the national institutes of health chronic prostatitis symptom index(NIH-CPSI)and international index of erectile function-5(IIEF-5)scores in the observation group were significantly higher than those in control group,and the number of cases of anxiety and depression was significantly higher,Chinese index of premature ejaculation-5(CIPE-5)scores were significantly lower than those of the control group,and the difference was statistically significant(P<0.05).Logistic regression analysis showed that age,disease course,severity of the disease,history of alcohol consumption,white blood cell count in prostatic fluid(>10/HP)and pelvic floor muscle tension were the influencing factors of secondary dysfunction in chronic prostatitis(P<0.05),and high NHI-CPSI scores,long disease course,pelvic floor muscle tension,and anxiety were the independent risk factors of secondary dysfunction in chronic prostatitis(P<0.05).Conclusions Secondary dysfunction in patients with chronic prostatitis are mostly characterized by old age,long disease course,more serious condition,and liking to drink alcohol,and the severity of symptoms,pelvic floor muscle tension,and mental anxiety are independent risk factors for chronic prostatitis secondary dysfunction.