阿奇霉素序贯给药辅助治疗小儿大叶性肺炎的效果及对患儿血清炎症因子水平的影响

Effect of Azithromycin sequential administration in the adjuvant treatment of lobar pneumonia in children and its influence on the level of serum inflammatory factors

目的探讨阿奇霉素序贯给药辅助治疗小儿大叶性肺炎的效果及对患儿血清炎症因子水平的影响。方法选取2021年2月至2023年4月昆山市第二人民医院收治的62例大叶性肺炎患儿作为研究对象,依据不同给药方式进行分组,接受阿奇霉素静脉滴注治疗的患儿纳入参照组(31例),接受阿奇霉素序贯给药辅助治疗的患儿纳入研究组(31例)。比较两组治疗总有效率、血清炎症因子水平以及不良反应总发生率。结果研究组治疗总有效率高于参照组(P<0.05);研究组血清炎症因子水平低于参照组(P<0.05);研究组不良反应总发生率低于参照组(P<0.05)。结论阿奇霉素序贯给药辅助治疗小儿大叶性肺炎的效果显著,能够减轻炎症反应,安全性高,值得推广。

Objective To investigate the effect of Azithromycin sequential administration in the adjuvant treatment of lobar pneumonia in children and its influence on the level of serum inflammatory factors.Methods A total of 62 children with lobar pneumonia in Kunshan Second People’s Hospital from February 2021 to April 2023 were selected as the study objects.According to different administration methods,children who received intravenous Azithromycin treatment were included in the reference group(31 cases),while who received Azithromycin sequential administration adjuvant treatment were included in the study group(31 cases).The total effective rate,serum inflammatory factor levels and total incidence of adverse reactions were compared between the two groups.Results The total effective rate in the study group was higher than that in the reference group(P<0.05).The levels of serum inflammatory factors in the study group were lower than those in the reference group(P<0.05).The total incidence of adverse reactions in the study group was lower than that in the reference group(P<0.05).Conclusion Azithromycin sequential administration in the adjuvant treatment of lobar pneumonia in children has si gnificant effect,which can reduce inflammation,has high safety,and is worth promoting.