2型糖尿病患者营养风险筛查及其影响因素分析

Nutritional risk screening and influencing factors in patients with type 2 diabetes

目的基于营养风险筛查2002(NRS2002)系统分析2型糖尿病患者的营养状况,研究患者营养风险的主要影响因素。方法选取2022年10月10日—2023年5月9日亳州市人民医院收治的糖尿病住院患者196例,根据有无营养风险分为有营养风险组(35例)和无营养风险组(161例)。分析患者的性别和相关生化指标(血红蛋白、糖化血红蛋白、白蛋白、总胆固醇、甘油三酯、尿素氮和肌酐)在有、无营养风险患者中的差异,采用多元logistic回归分析研究营养风险的独立影响因素。结果不同性别患者营养风险的发生差异无统计学意义(P>0.05)。相关临床生化检测结果显示,有营养风险的T2DM患者血清血红蛋白、白蛋白、尿素氮、肌酐分别为(122.29±10.07)g/L、(40.98±3.61)g/L、(6.97±0.16)mmol/L、(86.91±5.96)mmol/L,与无营养风险患者比较差异均有统计学意义[(128.15±9.96)g/L、(43.38±4.34)g/L、(5.81±0.92)mmol/L、(79.75±8.56)mmol/L,P<0.05];有、无营养风险患者糖化血红蛋白、总胆固醇及血清甘油三酯比较差异均无统计学意义(P>0.05)。多元logistic回归分析显示,血红蛋白、白蛋白和肌酐是T2DM患者发生营养风险的影响因素。结论应用NRS2002评估T2DM患者营养状况,血红蛋白、白蛋白和肌酐水平是T2DM患者发生营养风险的影响因素。

Objective To systematically analyze the nutritional status of type 2 diabetes(T2DM)patients based on nutrition risk screening(NRS2002),and screen the main impact indicators of nutritional risk.Methods A total of 196 T2DM patients were obtained from the People's Hospital of Bozhou between October 10,2022 and May 9,2023.The patients were divided into nutritional risk group(35 cases)and non-nutritional risk group(161 cases)based on the presence or absence of nutritional risk.Statistical analysis was used to investigate the differences in gender and related biochemical indicators(hemoglobin,glycated hemoglobin,albumin,total cholesterol,triglycerides,urea nitrogen,creatinine)between patients with and without nutritional risk.The independent influencing factors of nutritional risk were analyzed using multiple logistic regression analysis.Results There was no significant difference in the occurrence of nutritional risks between different genders(P>0.05).The relevant clinical biochemical test results showed that T2DM patients with nutritional risk had significant differences in serum hemoglobin[(122.29±10.07)g/L],albumin[(40.98±3.61)g/L],urea nitrogen[(6.97±0.16)mmol/L],and creatinine[(86.91±5.96)mmol/L]levels compared to non-nutritional risk patients[(128.15±9.96)g/L,(43.38±4.34)g/L,(5.81±0.92)mmol/L,(79.75±8.56)mmol/L,respectively,P<0.05].There was no significant difference in the statistics of glycated hemoglobin,total cholesterol,and serum triglycerides between patients with and without nutritional risk(P>0.05).Multiple logistic regression analysis was used to analyze hemoglobin,albumin,urea nitrogen,and creatinine.The results showed that hemoglobin,albumin,and creatinine were related risk factors for nutritional risk in T2DM patients.Conclusion NRS2002 is applied to assess the nutritional status of patients with T2DM,and haemoglobin,albumin and creatinine levels are influential factors in the occurrence of nutritional risk in patients with T2DM.