中西医结合综合治疗特发性矮小症的临床价值分析

Analysis of the clinical value of integrated treatment of traditional Chinese and Western medicine on children with idiopathic short stature

目的探讨分析对特发性矮小症患儿采用中西医结合综合治疗的临床疗效。方法90例特发性矮小症患儿开展本次研究,将所有患儿根据数字表法分为观察组与对照组,各45例。单独给予西医治疗的为对照组,采用中西医结合综合治疗的为观察组。比较两组的身高标准差及预测成年身高,消化系统及呼吸系统疾病的发生情况,生长因子水平。结果观察组身高标准差(-1.6±0.5)cm、预测成年身高(163.4±6.9)cm均优于对照组的(-1.9±0.7)、(156.7±5.4)cm(P<0.05)。观察组消化系统疾病发生率4.44%、呼吸系统疾病发生率8.89%均低于对照组的22.22%、28.89%(P<0.05)。观察组的胰岛素样生长因子-1为(195.5±25.8)ng/ml,胰岛素样生长因子结合蛋白-3为(4.4±0.8)μg/ml;对照组的胰岛素样生长因子-1为(104.5±16.8)ng/ml,胰岛素样生长因子结合蛋白-3为(2.4±0.4)μg/ml。观察组胰岛素样生长因子-1、胰岛素样生长因子结合蛋白-3均高于对照组(t=19.828、15.000,P=0.000、0.000<0.05)。结论对特发性矮小症患儿采用中西医结合综合治疗的临床疗效更为确切,可以使患儿的身高大幅增长,并提高患儿的自身免疫力,有必要在临床上大力推广。

Objective To explore and analyze the clinical efficacy of integrated treatment of traditional Chinese and Western medicine on children with idiopathic short stature.Methods A total of 90 children with idiopathic short stature were selected for this study.All children were divided into a observation group and a control group according to the number table method,with 45 cases in each group.The control group was treated with Western medicine alone,and the observation group was treated with integrated treatment of traditional Chinese and Western medicine.The standard deviation of height,the prediction of adult height,incidence of digestive system and respiratory system diseases,growth factor levels of the two groups were compared.Results The standard deviation of height and the prediction of adult height in the observation group were(-1.6±0.5)and(163.4±6.9)cm,which were better than(-1.9±0.7)and(156.7±5.4)cm in the control group(P<0.05).The incidence rates of digestive system and respiratory system diseases in the observation group were 4.44%and 8.89%,which were lower than 22.22%and 28.89%in the control group(P<0.05).In the observation group,the levels of insulin-like growth factor-1 and insulin-like growth factor-binding protein-3 were(195.5±25.8)ng/ml and(4.4±0.8)μg/ml,respectively.In the control group,the levels of insulin-like growth factor-1 and insulin-like growth factor-binding protein-3 were(104.5±16.8)ng/ml and(2.4±0.4)μg/ml respectively.The levels of insulin-like growth factor-1 and insulin-like growth factor-binding protein-3 in the observation group were higher than those in the control group(t=19.828,15.000;P=0.000,0.000<0.05).Conclusion The combined treatment of traditional Chinese and Western medicine has more definite clinical effect on children with idiopathic short stature,which can greatly increase their height and improve their immunity.It is necessary to promote it in clinic.