输尿管镜下钬激光碎石术与气压弹道碎石术治疗输尿管结石患者的效果比较

Comparison of effects of ureteroscopic holmium laser lithotripsy and pneumatic lithotripsy in treatment of patients with ureteral calculi

目的:观察输尿管镜下钬激光碎石术与气压弹道碎石术治疗输尿管结石患者的效果。方法:回顾性分析2019年11月至2022年10月该院收治的64例输尿管结石患者的临床资料,根据治疗方式不同将其分为研究组和对照组各32例。对照组予气压弹道碎石术治疗,研究组予输尿管镜下钬激光碎石术治疗,比较两组一次性结石清除率、手术时间、住院时间、术后并发症发生率、炎性指标和肾功能指标水平。结果:研究组一次性结石清除率和上段结石清除率均高于对照组,手术时间和住院时间均短于对照组,术后并发症发生率,血清C反应蛋白、白细胞计数、血清尿素氮和肌酐水平均低于对照组,差异有统计学意义(P<0.05)。结论:钬激光碎石术治疗输尿管结石患者,可有效提高一次性结石清除率,缩短手术时间和住院时间,并可减少术后并发症,降低炎性指标及肾功能指标水平,其临床效果优于气压弹道碎石术。

Objective:To observe effects of ureteroscopic holmium laser lithotripsy and pneumatic lithotripsy in treatment of patients with ureteral calculi.Methods:The clinical data of 64 patients with ureteral calculi admitted to the hospital from November 2019 to October 2022 were retrospectively analyzed.According to different treatment methods,they were divided into study group and control group,32 cases in each group.The control group was treated with pneumatic lithotripsy,while the study group was treated with ureteroscopic holmium laser lithotripsy.The one-time stone clearance rate,the operation time,the hospitalization time,the postoperative complications,and the levels of inflammatory indexes and renal function indexes were compared between the two groups.Results:The one-time stone clearance rate and the upper stone clearance rate in the study group were higher than those in the control group;the operation time and the hospitalization time were shorter than those of the control group;the incidence of complications after the treatment was lower than that of the control group;the serum C-reactive protein,white blood cell count,serum urea nitrogen and creatinine levels were lower than those in the control group;and the differences were statistically significant(P<0.05).Conclusions:Holmium laser lithotripsy for the patients with ureteral calculi can effectively improve the one-time stone clearance rate,shorten the operation time and the hospitalization time,reduce the postoperative complications,and reduce the levels of inflammatory indexes and renal function indexes.Moreover,it is superior to pneumatic lithotripsy.