2012—2021年归因于大气PM_(2.5)的苏州市脑卒中早死寿命损失分析

Analysis on life loss of stroke early death attributed to atmospheric PM_(2.5)in Suzhou City from 2012 to 2021

目的对2012—2021年归因于大气细颗粒物(fine particulate matter,PM_(2.5))暴露的苏州市脑卒中疾病负担进行分析。方法采用2019年全球疾病负担研究(global burden of disease 2019,GBD2019)数据,分析死亡数、死亡率、早死寿命损失年(years of life lost,YLL)和每千人寿命损失年(YLL率)来分析归因于PM_(2.5)的苏州市脑卒中早死寿命损失情况。结果2012—2021年苏州市25岁以上人群因脑卒中导致的死亡人数、死亡率、YLL和YLL率均呈现上升趋势(均P<0.01);归因于PM_(2.5)的脑卒中死亡人数累计26513例,YLL为402215人年,YLL率为7.45‰,均为男性显著高于女性。随着年份的增加,归因PM_(2.5)的脑卒中死亡人数、YLL和YLL率均呈现下降趋势(均P<0.01)。如果苏州市维持在国家一级标准水平(15μg/m^(3)),则在过去10年可以减少脑卒中死亡13541人、YLL 201689人年。结论归因于PM_(2.5)的脑卒中寿命损失严重危害苏州市居民健康,其疾病负担在不同性别、年龄人群中存在差异。随着大气PM_(2.5)不断降低,归因于PM_(2.5)的脑卒中疾病负担不断下降,进一步改善空气质量对提高居民健康具有重要意义。

Objective To analyze the burden of stroke in Suzhou City from 2012 to 2021 attributed to exposure to fine particulate matter(PM_(2.5))in the atmosphere.Methods The 2019 Global Burden of Disease(GBD2019)data was used to analyze the number of deaths,mortality rate,years of life loss(YLL),and years of life loss per thousand people(YLL rate)attributed to PM_(2.5)in early stroke life loss in Suzhou City.Results The number of deaths,mortality rate,YLL,and YLL rates caused by stroke among the population aged 25 and above in Suzhou City showed an increasing trend from 2012 to 2021(all P<0.01).The cumulative number of stroke deaths attributed to PM_(2.5)was 26513,with a YLL of 402215 person years and a YLL rate of 7.45‰,both of which were significantly higher in males than females.With the increase of years,the number of stroke deaths attributed to PM_(2.5),as well as the YLL and YLL rates,showed a decreasing trend(all P<0.01).If Suzhou City maintained at the national first level standard level(15μG/m^(3)),it could reduce stroke deaths by 13541 people and YLL by 201689 people per year in the past decade.Conclusions It is that stroke life loss attributed to PM_(2.5)seriously endangers the health of residents in Suzhou,and the disease burden varies among different genders and age groups.As atmospheric PM_(2.5)continues to decrease,the burden of stroke attributed to PM_(2.5)continues to decrease.Further improving air quality is of great significance for improving the health of residents.