氨溴索治疗小儿支气管肺炎的临床效果分析

Analysis of clinical effect of ambroxol in treatment of bronchopneumonia in children

目的:探讨氨溴索联合头孢呋辛钠治疗小儿支气管肺炎的临床效果。方法:选择2020年10月至2022年6月医院接收的小儿支气管肺炎患儿96例,采用随机数字表法分为对照组和观察组(n=48)。对照组采用头孢呋辛钠治疗,观察组采用氨溴索联合头孢呋辛钠治疗,治疗7 d后记录患者发热、咳嗽等症状消失时间,并采用血液分析仪、免疫扩散法测定白细胞技术和C-反应蛋白(C-reactive protein,CRP),对比两组患者总有效率。结果:观察组发热、咳嗽、肺部湿啰音等临床症状消失时间均显著短于对照组(P<0.05)。治疗前,两组的白细胞计数、CRP水平均无显著差异(P>0.05)。治疗7 d后两组白细胞计数、CRP水平均低于治疗前,且观察组低于对照组(P<0.05)。观察组治疗总有效率为显著高于对照组(P<0.05)。结论:氨溴索联合头孢呋辛钠治疗能促进小儿支气管肺炎患儿的临床症状消失,降低小儿支气管肺炎患儿机体炎症反应。

Objective:To investigate the clinical effect of ambroxol combined with cefuroxime sodium in the treatment of children with bronchial pneumonia.Methods:A total of 96 children with bronchopneumonia were selected from October 2020 to June 2022 and divided into control group and observation group by random number table method(n=48).The control group was treated with cefuroxime sodium,and the observation group was treated with ambroxol combined with cefuroxime sodium.After 7 days of treatment,the disappearance time of fever,cough and other symptoms of the patients was recorded,and leukocytes technology and C-reactive protein(CRP)were measured by hematology analyzer and immunodiffusion method.The total effective rate of the two groups was compared.Results:The disappearance time of fever,cough,lung moist rales and other clinical symptoms in observation group was significantly shorter than that in control group(P<0.05).Before treatment,there were no significant differences in white blood cell count and CRP levels between the two groups(P>0.05).After 7 days of treatment,the white blood cell count and CRP level of the two groups were lower than before treatment,and the observation group was lower than the control group(P<0.05).The total effective rate of observation group was significantly higher than that of control group(P<0.05).Conclusion:Ambroxol combined with cefuroxime sodium can promote the disappearance of clinical symptoms and reduce the inflammatory response of children with bronchopneumonia.