合成生物学驱动再生医学创新:从细胞工程到器官修复

Synthetic biology is driving regenerative medicine innovation:From cell engineering to organ repair

随着合成生物学的快速发展,其与再生医学的结合后,为细胞工程和器官修复开辟了新的途径。合成生物学的技术可用于精确修复基因缺陷,将成体细胞重编程为诱导多能干细胞后进行定向分化,可用于患者自身细胞的再生医学治疗。此外,合成生物学还可应用于设计组织工程材料和三维打印人工器官。尽管存在生物安全等方面的挑战,但合成生物学的发展将推动再生医学向精准化方向发展,实现个体化治疗。合成生物学与再生医学的跨学科合作,将有助于各项核心技术得到进一步提升与创新,对再生医学的发展意义重大。

With the rapid development of synthetic biology,its combination with regenerative medicine has opened up new pathways for cell engineering and organ repair.Synthetic biology techniques can be used to precisely repair genetic defects,reprogram mature cells into induced pluripotent stem cells,and perform targeted differentiation for regenerative medical treatment of patients'own cells.In addition,synthetic biology can also be applied to design tissue engineering materials and 3D printing artificial organs.Despite the challenges such as biosafety and ethics,the progress in synthetic biology will drive the development of regenerative medicine towards precision and personalized treatment.The convergence of synthetic biology and regenerative medicine will facilitate further improvements and innovations in various core technologies for the advancement of regenerative medicine.