柳暗花明:胞外生长素信号感受的新突破

There Is a Way Out-new Breakthroughs in Extracellular Auxin Sensing

生长素在植物生长发育过程中发挥重要作用,其信号转导机制一直是植物学领域关注的热点。前期研究表明,ABP1-TMK分子模块参与胞外生长素信号感受,但ABP1作为生长素受体备受争议。近期,福建农林大学徐通达团队和杨贞标团队鉴定到ABL蛋白作为生长素结合蛋白参与胞外生长素信号感受。与传统的功能冗余不同,ABL和ABP1通过蛋白结构的相似性实现功能补偿效应,进而与TMK在细胞膜上形成复合体,作为胞外生长素的共受体介导生长素信号驱动的快速反应。该研究深入解析了胞外生长素信号感受的重要机制,是生长素研究领域的重大突破。

Auxin plays an important role in plant growth and development and its signal transduction has always been the focus of attention in the field of plant biology.AUXIN BINDING PROTEIN 1(ABP1)-TRANSMEMBRANE KINASE(TMK)molecular module is involved in the extracellular auxin perception.In recent years,ABP1 has been controversial as an auxin receptor.Recently,Tongda Xu’s team and Zhenbiao Yang’s team from Fujian Agriculture and Forestry University identified ABP1-LIKE PROTEIN(ABL)as the auxin binding proteins involved in the extracellular auxin perception.Different from traditional functional redundancy,ABL and ABP1 achieve functional compensation effect through protein structure similarity,and then form complex with TMK at the plasma membrane,acting as co-receptors of apoplastic auxin to mediate auxin driven rapid response.This study deeply dissects the mechanism of extracellular auxin sensing,which is a breakthrough in the field of auxin signaling transduction.