糖尿病肾病患者心脏结构与功能研究进展

Research progress of cardiac structure and function in patients with diabetic nephropathy

糖尿病肾病(DN)是糖尿病微血管最常见的并发症之一。DN患者往往伴发心血管疾病。DN患者随着蛋白尿升高、肾小球滤过率下降及血肌酐水平的升高常伴发心脏功能、结构的改变,导致心血管疾病的发生。另外炎症因子对心脏结构与功能影响也具有重要作用,深入了解炎症在DN心血管疾病的病理生理作用,明确DN患者心脏结构与功能关系,对其预防和治疗具有重要意义。

Diabetic nephropathy(DN)is a common microvascular complication of diabetes mellitus.Cardiovascular disease often occurs in patients with DN.Patients with DN often experience changes in cardiac structure and function as proteinuria increases,glomerular filtration rate decreases,and blood creatinine levels increase,leading to the occurrence of cardiovascular disease.Additionally,inflammatory factors play a crucial role in cardiac structure and function.Understanding the pathological and physiological effects of inflammation on diabetic nephropathy-related cardiovascular disease and clarifying the relationship between cardiac structure and function in patients with DN are crucial for effective prevention and treatment of DN.