中国角膜内皮移植术专家共识(2024年)

Chinese expert consensus on corneal endothelial transplantation(2024)

角膜内皮移植术是治疗角膜内皮疾病的重要方法,主要分为角膜后弹力层剥除内皮移植术和角膜后弹力层内皮移植术。与穿透性角膜移植术比较,角膜内皮移植术的术后视力好,免疫排斥反应发生率低,但手术技术和过程较为复杂,术中和术后并发症有所不同。角膜内皮移植术的成功关键在于掌握手术的基本要素并预防并发症。为在我国规范开展和推广角膜内皮移植术,中华医学会眼科学分会角膜病学组以国内外研究结果和临床实践经验为基础,围绕角膜内皮移植术的适应证、术前评估、手术技术和操作、术后并发症处理和随访等进行充分讨论,达成共识性意见,以期为临床工作提供指导和参考。

Endothelial keratoplasty(EK)is an effective therapy for corneal endothelial diseases and mainly includes Descemet stripping endothelial keratoplasty and Descemet membrane endothelial keratoplasty.Compared with penetrating keratoplasty,EK has better vision rehabilitation and a lower rate of allograft rejection after surgery.However,EK poses a series of technical challenges,and varied complications may occur intraoperatively and postoperatively.A successful EK surgery depends on the standardized technical manipulations and the management of surgical complications.In order to standardize the surgical procedure of EK in China,the Cornea Group of Ophthalmology Branch of Chinese Medical Association has made a comprehensive discussion about indications of surgery,preoperative evaluation,surgical manipulations,and the management of complications based on the literature available thus far and clinical practice in China,and eventually established this consensus,which may guide corneal surgeons in performing the EK surgery.