张声生“调态消癥”辨治慢性萎缩性胃炎及胃癌前病变创新思路构建及运用

Construction and application of ZHANG Shengsheng's innovative ideas to differentiate and treat chronic atrophic gastritis and precancerous lesions of gastric cancer through‘Tiaotai Xiaozheng'

慢性萎缩性胃炎(CAG)及胃癌前病变(PLGC)是消化系统的常见病及疑难病,深化对CAG及PLGC病因病机的认识既能丰富中医理论研究体系,更有助于指导临床治疗。张声生教授临证论治CAG及PLGC经验丰富,总结本病“五态一癥”病机学说,即“虚、浊、滞、瘀、毒、癥”。其中脾胃虚弱是根本病机,浊、滞、瘀、毒交结是CAG及PLGC重要的病变状态,癥是疾病的靶标。基于此病机,张声生教授系统总结“调态消癥”理论,包括“调虚态、调浊态、调滞态、调瘀态、调毒态、消癥积”,以期对本病的辨治论治提供新的思路。

Chronic atrophic gastritis(CAG)and precancerous lesions of gastric cancer(PLGC)are common and difficult diseases of the digestive system.Deepening the understanding of the etiology and pathogenesis of CAG and PLGC can not only enrich the theoretical research system of traditional Chinese medicine,but also help to guide clinical treatment.Professor ZHANG Shengsheng has rich experience in the treatment of CAG and PLGC,and summarizes the key pathogenesis of CAG and PLGC as‘Five main states and key Zheng masses',namely'deficiency,turbidity,stagnation,stasis,toxin and Zheng masses'.Weakness of the spleen and stomach is the fundamental pathogenesis;Turbidity,stagnation,stasis and toxins are the important pathological conditions of CAG and PLGC;Zheng masses is the target of the disease.Based on this pathogenesis,professor ZHANG Shengsheng puts forward six methods of syndrome differentiation and treatment,namely Five main states and key Zheng masses,including'regulating deficiency state,regulating turbidity state,regulating stagnation state,regulating stasis state,regulating toxin state and eliminating Zheng masses',to provide new thinking for the syndrome differentiation and treatment of this disease.