体外膜肺氧合患者功能锻炼的最佳证据总结

Summary of the best evidence for functional exercise in patients on extracorporeal membrane oxygenation therapy

目的总结体外膜肺氧合患者功能锻炼的最佳证据,为制定科学的体外膜肺氧合患者功能锻炼方案提供参考。方法系统检索国内外相关指南网站、循证数据库、相关协会网站及学术文献数据库等关于体外膜肺氧合患者功能锻炼的相关证据。检索时限为建库至2023年6月。由2名经过循证医学方法学培训的研究人员对所纳入的文献进行质量评价。结果共纳入12篇文献,包括指南2篇,系统评价5篇,专家共识3篇,随机对照试验2篇。最终提取出了前期准备、评估、运动方法和安全监测4个方面共35条最佳证据。结论总结的最佳证据可为开展体外膜肺氧合患者功能锻炼提供依据,从而为患者提供个性化的康复训练方案。

Objective To retrieve and summarize the best evidence of functional exercise in patients on extracorporeal membrane oxygenation(ECMO)therapy,so as to provide a reference for formulating a scientific functional exercise program for these patients.Methods We systematically searched relevant guideline websites,evidence-based databases,websites of relevant associations and academic databases at home and abroad for evidence on functional exercise in patients on ECMO therapy.The search time limit was from the establishment of the database to June 2023.Two researchers trained in evidence-based medicine methodology evaluated the quality of the included literature.Results A total of 12 articles were included,including 2 guidelines,5 systematic reviews,3 expert consensus reports,and 2 randomized controlled trials.Finally,a total of 35 pieces of best evidence were extracted from 4 aspects,including preparation in advance,evaluation,exercise implementation and safety monitoring.Conclusion The best evidence summarized can provide the basis for carrying out limb functional exercise for patients on ECMO therapy,so as to provide patients with personalized rehabilitation training programs.