急性心肌梗死PCI术后24 h内发生心衰及1个月后未缓解的相关因素分析

Analysis of related factors of heart failure within 24 h after PCI and non-remission after 1 month in acute myocardial infarction

目的探讨急性心肌梗死经皮冠状动脉介入治疗术(PCI)术后24 h内发生心衰及1个月后未缓解的相关因素。方法选取我院2020年1月~2023年1月收治的98例急性心肌梗死行PCI的患者作为研究对象,治疗1个月后进行随访,按照患者心衰缓解的情况分为心衰组(n=25)和非心衰组(n=73)。对比两组患者的一般资料和相关指标,采用单因素和多因素Logistic回归分析影响术后心衰未缓解的因素。结果心衰组多支血管病变占比、左前降支病变占比及血管开通时间均多于非心衰组(P<0.05),心衰组单支血管病变占比、右冠病变占比均少于对照组(P<0.05),其他指标两组对比差异无统计学意义(P>0.05);多因素Logistic回归分析结果显示,多支血管病变、左前降支病变、血管开通时间延长为急性心肌梗死PCI术后24h内出现心衰及1个月后未缓解的独立危险因素(P<0.05)。结论多支血管病变、左前降支病变、血管开通时间延长为急性心肌梗死PCI术后24 h内发生心衰及1个月后未缓解的独立危险因素。

Objective To investigate the related factors of heart failure within 24 h after percutaneous coronary intervention(PCI)and non-remission after 1 month in patients with acute myocardial infarction.Methods A total of 98 patients with acute myocardial infarction who underwent PCI in our hospital from January 2020 to January 2023 were selected as the study objects.After 1 month of treatment,they were followed up and divided into heart failure group(n=25)and non-heart failure group(n=73)according to the remission of heart failure.The general data and related indicators of the two groups were compared,and the factors affecting the non-remission of postoperative heart failure were analyzed by univariate and multivariate Logistic regression.Results The proportion of multi-vessel disease,the proportion of left anterior descending artery disease and the opening time of blood vessels in the heart failure group were more than those in the non-heart failure group(P<0.05).The proportion of single-vessel disease and right coronary artery disease in the heart failure group were less than those in the control group(P<0.05).There was no significant difference in other indicators between the two groups(P>0.05).Multivariate Logistic regression analysis showed that multivessel disease,left anterior descending artery disease,and prolonged vascular opening time were independent risk factors for heart failure within 24 h after PCI in acute myocardial infarction and no remission after 1 month(P<0.05).Conclusion Multivessel disease,left anterior descending artery disease,and prolonged vascular opening time are independent risk factors for heart failure within 24 h after PCI in acute myocardial infarction and non-remission after 1 month.