止痒息风汤治疗老年湿疹皮肤瘙痒合并失眠的临床研究

Clinical Study on the Treatment of Elderly Eczema Skin Itching Combined with Insomnia with Zhiyang Xifeng Tang

目的:观察止痒息风汤治疗老年湿疹皮肤瘙痒合并失眠的临床疗效。方法:选取2021年3月至2023年3月福建省福州市福其祥中医院中医外科收治的老年湿疹皮肤瘙痒合并失眠患者92例作为研究对象,以随机数字表法分为对照组和观察组,每组46例。2组均接受基础治疗,对照组接受枸地氯雷他定治疗,观察组在对照组基础上接受止痒息风汤治疗。2组均治疗4周。比较2组中医证候评分、睡眠质量、不良反应及临床疗效。结果:治疗后,2组中医证候主症、次症评分均较本组治疗前降低(P<0.05),且观察组治疗后较对照组更低(P<0.05)。治疗后,2组瘙痒面积、苔藓化程度、瘙痒程度评分较本组治疗前均降低(P<0.05),且观察组治疗后低于对照组(P<0.05)。观察组总有效率(97.83%)高于对照组(86.96%,P<0.05)。治疗后,2组匹兹堡睡眠质量指数量表(PSQI)评分、阿森斯失眠量表(AIS)评分较本组治疗前均降低(P<0.05),且观察组治疗后低于(P<0.05)。2组不良反应总发生率比较差异无统计学意义(P>0.05)。结论:止痒息风汤治疗老年湿疹皮肤瘙痒合并失眠疗效确切,可改善患者临床症状,提升睡眠质量,且安全可靠。

Objective:To observe the clinical efficacy of Zhiyang Xifeng Tang in treating elderly eczema with skin itching and insomnia.Methods:A total of 92 elderly patients with eczema,skin itching,and insomnia admitted to the Department of Traditional Chinese Medicine at Fuqixiang Traditional Chinese Medicine Hospital in Fuzhou City,Fujian Province from March 2021 to March 2023 were selected as the study subjects.They were randomly divided into an observation group and a control group,with 46 cases in each group,using a random number table method.Both groups received basic treatment,the control group received treatment with loratadine,and the observation group received treatment with Zhiyang Xifeng Tang on the basis of the control group.Both groups were treated for 4 weeks.Compare the TCM syndrome scores,sleep quality,adverse reactions,and clinical efficacy between two groups.Results:After treatment,the scores of the main and secondary symptoms of traditional Chinese medicine in both groups decreased compared to before treatment in this group(P<0.05),and the observation group was lower than the control group after treatment(P<0.05).After treatment,the itching area,degree of mossification,and itching score of both groups decreased compared to before treatment(P<0.05),and the observation group was lower than the control group after treatment(P<0.05).The total effective rate of the observation group(97.83%) was higher than that of the control group(86.96%,P<0.05).After treatment,the Pittsburgh Sleep Quality Index(PSQI) score and the Asens Insomnia Scale(AIS)score of both groups decreased compared to before treatment in this group(P<0.05),and the observation group decreased after treatment(P<0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion:Zhiyang Xifeng Tang has a definite therapeutic effect on elderly patients with eczema,skin itching,and insomnia.It can improve clinical symptoms,enhance sleep quality,and is safe and reliable.