低频脉冲电刺激联合桃红四物汤保留灌肠对慢性盆腔炎合并盆腔积液的疗效

Effects of low-frequency electric stimulation combined with Taohong Siwu Decoction for retention enema on the efficacy of chronic pelvic inflammation combined with pelvic effusion

目的探讨低频脉冲电刺激联合桃红四物汤保留灌肠治疗慢性盆腔炎合并盆腔积液的疗效及对血清炎性因子的影响。方法选取380例慢性盆腔炎合并盆腔积液患者,按随机数字表法分为研究组和对照组,每组190例。对照组治疗方案为西药抗炎治疗,研究组为低频脉冲电刺激联合桃红四物汤保留灌肠。比较2组实际治疗效果,血性炎性因子[D-二聚体(D-D)、超敏C-反应蛋白(hs-CRP)、白介素-6(IL-6)]水平。结果研究组总有效率高于对照组(P<0.05);2组治疗前中医证候积分比较差异无统计学意义(P>0.05);2组治疗1~4周后中医证候积分均低于本组治疗前(P<0.05);且研究组治疗后1、2、4周中医证候积分均低于对照组(P<0.05);2组治疗前症状表现比较差异无统计学意义(P>0.05),治疗后2组盆腔痛、盆腔包块、盆腔积液、附件增粗等症状均有所好转,其中研究组各症状消失或减轻人数高于对照组(P<0.05);2组治疗前炎性因子水平比较差异无统计学意义(P>0.05);治疗后,研究组D-D、hs-CRP、IL-6水平均低于对照组(P<0.05);治疗前2组患者生活质量差异无统计学意义(P>0.05),2组治疗后生活质量各维度评分均有所提升,但研究组升高幅度大于对照组(P<0.05)。结论低频脉冲电刺激联合桃红四物汤保留灌肠治疗慢性盆腔炎合并盆腔积液的疗效显著,降低患者机体的炎性因子水平,改善临床症状。

Objective To discuss the low-frequency electric stimulation and Taohong Siwu Decoction for retention enema on the efficacy of chronic pelvic inflammation combined with pelvic effusion and inflammatory factor levels.Methods A total of 380 cases of chronic pelvic inflammation combined with pelvic effusion treated in our outpatient and inpatient departments were selected.The patients were randomly divided into study group(n=190)and control group(n=190).The Western medicine was applied in the control group,and the low-frequency electric stimulation combined with Taohong Siwu Decoction for retention enema was applied in the study group.Treatment outcomes were analyzed.Results The total effective rate in the study group was significantly higher than that of control group(P<0.05).Before treatment,there were no significant differences in the traditional Chinese medicine(TCM)syndrome scores between groups(P>0.05).After 1-4 weeks of treatment,TCM syndrome scores were significantly reduced in both groups,which,at 1,2 and 4 weeks,were significantly lower in the study group than those of control group(P<0.05).Before treatment,there were no significant difference in the clinical symptoms between groups(P>0.05).After treatment,the clinical symptoms of pelvic cavity pain,pelvic inflammatory mass,pelvic effusion and pelvic appendage in both groups were significantly alleviated,and the case number of symptom disappearance orrelief was significantly higher in the study group than that of control group(P<0.05).Before treatment,there were no significant differences in the inflammatory factors between groups(P>0.05).After treatment,D-dimeR(D-D),hypersensitivity C-reactive protein(hs-CRP)and interleukin-6(IL-6)levels in the study group were significantly lower than those of control group(P<0.05).Before treatment,there were no significant differences in the life quality scores between groups(P>0.05).After treatment,the Nottingham health profile(NHP)scores in both groups were significantly higher than those before,which were significantly higher in the study group than those of control group(P<0.05).Conclusion The low-frequency electric stimulation and Taohong Siwu Decoction for retention enema can effectively reduce the inflammatory factors and improve clinical symptoms,improve the efficacy and safety for patients with chronic pelvic inflammation combined with pelvic effusion,with significant clinical application value.