摘要
直肠癌是我国常见恶性肿瘤,死亡率高居第5位。直肠癌新辅助治疗可以改善患者预后,甚至可使部分患者达到病理学完全缓解(pCR),从而避免根治性手术带来的并发症和功能损害,因此,如何在术前准确评估pCR是目前的研究热点。近年来包括直肠腔内超声、MRI、正电子发射计算机断层显像(PET-CT)等在内的影像新技术快速发展,影像学评估直肠癌新辅助治疗后pCR已取得了良好效果。本文对这一领域进行综述,旨在为直肠癌患者个性化治疗提供依据。
Rectal cancer is a common malignant tumor in China,with a high mortality rate ranking fifth.Neoadjuvant therapy for rectal cancer can improve patient prognosis and even achieve pathological complete remission(pCR)in some patients,thereby avoiding complications and functional damage caused by radical surgery.Therefore,how to accurately evaluate pCR before surgery is currently a research hotspot.In recent years,new imaging technologies such as endorectal ultrasound,magnetic resonance imaging(MRI),and positron emission computed tomography(PET-CT)have developed rapidly,and imaging evaluation of pCR after neoadjuvant therapy for rectal cancer has achieved good results.This article provides a review of this field,aiming to provide a basis for personalized treatment of rectal cancer patients.
作者
王丽瑞
吴国柱
Wang Lirui;Wu Guozhu(Graduate School of Baotou Medical College,Inner Mongolia University of Science and Technology,Baotou 014040,China;Department of Ultrasound,Inner Mongolia Autonomous Region People′s Hospital,Hohhot 010017,China)
出处
《中国医师杂志》
CAS
2024年第2期306-310,共5页
Journal of Chinese Physician
基金
内蒙古自治区自然科学基金(2021MS08034)
内蒙古医学科学院公立医院科研联合基金科技项目(2023GLLH0075)。
关键词
直肠肿瘤
新辅助治疗
病理学完全缓解
影像学检查
Rectal neoplasms
Neoadjuvant therapy
Pathological complete response
Imaging examination