SGLT2i对糖尿病心肌保护作用及机制研究进展

Research progress of protective effect and mechanism of SGLT2i on diabetic cardiomyopathy

钠-葡萄糖协同转运蛋白-2抑制剂(SGLT2i)是新型的降糖药物,通过其独特的降糖机制来调整患者的血糖。目前的很多研究发现SGLT2i在降低血糖的同时也能使患者的心功能受益,但是目前其作用机制尚未完全明确,本文对其相关机制的研究进展进行综述。

Sodium-glucose co-transporter protein-2 inhibitors(SGLT2i)are novel hypoglycaemic agents that regulate patients'blood glucose through their unique hypoglycaemic mechanisms.Many current studies have found that SGLT2i can benefit patients'cardiac function while lowering blood glucose,but the mechanism of action is not yet fully clear,and this article provides a review of the progress of research on its related mechanisms.