不同形式高原训练对运动员免疫功能及抗氧化能力标志物影响的网状Meta分析

Network Meta analysis of different form effects of altitude training on immune function and antioxidant capacity markers of athletes

[目的]探讨不同形式高原训练对运动员免疫功能及抗氧化能力标志物的影响效应.[方法]检索国内外权威数据库关于运动员参与高原训练的研究文献.[结果]网状Meta分析显示与常规训练比较,1)高住高练、高住高练低训及高住低练可显著提高运动员白细胞水平;2)高住高练、高住低练及间歇性低氧训练可显著提高运动员CD4^(+)/CD8^(+)水平;3)高住高练较低住低练可显著提高运动员血清肌酸激酶水平;4)间歇性低氧训练及低住高练可显著降低运动员血清丙二醛水平;5)高住高练,高住高练低训,高住低练及低住高练可显著降低运动员血清超氧化物歧化酶水平.[结论]高原训练可能显著抑制运动员免疫功能及抗氧化能力,间歇性低氧训练对运动员白细胞计数影响最显著,高住低练最易诱发CD4^(+)/CD8^(+)失衡,低住高练最易导致丙二醛功能受损,高住高练对血清肌酸激酶和超氧化物歧化酶的影响最显著.

[Objective]To explore the effects of different forms of altitude training on immune function and antioxidant markers of athletes.[Methods]The international authoritative databases were searched.[Results]The network Meta-analysis compared with LoLo during training showed that:1)HiHi and HiLo can significantly improve the WBC level;2)HiHi,HiLo and IHT significantly increased the level of CD4^(+)/CD8^(+);3)HiHi can significantly improve the serum CK level;4)IHT and LoHi significantly reduced the serum MDA level;5)HiHi,HiHiLo,HiLo and LoHi can significantly reduce the serum SOD level.[Conclusion]Altitude training may significantly inhibit the immune function and antioxidant capacity of athletes,IHT has the most significant effect on WBC count of athletes,HiLo is the most likely to induce CD4^(+)/CD8^(+)imbalance,LoHi is the most likely to cause MDA function damage,HiHi has the most profound effect on serum CK and SOD.