脉血康胶囊(肠溶片)治疗心脑血管疾病临床应用专家共识

Expert Consensus for Clinical Application of Maixuekang Capsule(Enteric-Coated Tablet)(脉血康胶囊)in Treatment of Cardiovascular and Cerebrovascular Diseases

脉血康胶囊(肠溶片)治疗心脑血管疾病具有良好的临床疗效及安全性。在临床医生问卷调查和脉血康胶囊(肠溶片)研究文献系统回顾的基础上,采用国际临床医学专家共识研制方法,基于现有最佳证据,充分结合专家经验,遵循“循证为主,共识为辅,经验为鉴”的原则,国内26位中西医临床、药学、方法学等多学科专家共同研制该共识,旨在进一步提高临床医生对该药的认识,更好地指导其临床合理用药。共识采用国际公认的证据分级推荐标准即评估、发展和评价建议的分级(Grading of Recommendations Assessment,Development and Evaluation,GRADE分级),如果证据充分则形成“推荐意见”,采用GRADE网格计票规则;如果证据不充分,则形成“共识建议”,采用多数计票规则。共识对脉血康胶囊(肠溶片)用于心脑血管疾病的适应证、用法用量、疗程、禁忌证、合并用药进行了推荐或建议,并完善了安全性信息,为其临床的合理使用提供参考。

Maixuekang Capsule(Enteric-Coated Tablet)(脉血康胶囊)has good clinical efficacy and safety when used in cardiovascular and cerebrovascular diseases.Based on questionnaire investigation of doctors and a systematic review of research literature on Maixuekang Capsule(enteric-coated tablet),using international clinical practice guidelines developing methods,with the best available evidence and fully combining expertsexperience,and following the“evidence-based,consensus-based and experience-based”principle,the expert consensus statement on Maixuekang Capsule(Enteric-Coated Tablet)in clinical practice was developed by 26 multidisciplinary experts from the nationwide,aimed at guiding and standardizing the rational use of Maixuekang Capsule(Enteric-Coated Tablet).The expert consensus adopted internationally recognized recommendation criteria for classification of evidence:Grading of Recommendations Assessment,Development and Evaluation(GRADE).If there was sufficient evidence,a“recommendation”was formed,using GRADE grid voting rule.If there was no sufficient evidence,a“consensus opinion”was formed,using majority counting rule.The expert consensus focused on the indication,usage and dosage,treatment course,contraindication,concomitant medication and safety of Maixuekang Capsule(Enteric-Coated Tablet)when used in cardiovascular and cerebrovascular diseases,and provided guidance and reference for the rational use of Maixuekang Capsule(Enteric-Coated Tablet).