多花黄精活性成分研究进展

Research Progress on Active Ingredients of Polygonatum Cyrtonema Hua

目的解决多花黄精目前主要是其传统药用部位根用作保健食材直接食用,而有着类似功效成分的地上部分茎叶全部作为废弃物丢弃,多花黄精功效成分及其作用机制的研究严重不足等困境;明确多花黄精资源的研发方向。方法通过广泛调研文献、分析多花黄精的研究现状,对多花黄精中各类化学成分的组成、含量、结构和活性及其作用机制,多花黄精总多糖、总皂苷和总黄酮等主要化学成分不同产地、不同龄节、不同生境、不同部位的含量差异,以及总黄酮提取工艺等进行了综述。结果多花黄精具有降血糖、抗疲劳、提高免疫力、抗肿瘤、抗菌、抗病毒、抗凝血和抗抑郁等多种生物活性,且其主要功效成分为多糖、皂苷、黄酮和生物碱等。结论不同产地、不同龄节、不同生境的多花黄精其总多糖、总皂苷和总黄酮含量差异明显,地上部分也存在总多糖、总皂苷和总黄酮等功效成分,今后应加强对多花黄精资源的深度研究和开发,充分利用多花黄精资源。

Objective Currently,the main traditional medicinal part of Polygonatum cyrtonema Hua is its roots,which are used as a health food ingredient for direct consumption,while the aboveground stems and leaves,which have similar effects,are all discarded as waste.This paper aims to find the potential of aboveground parts of Polygonatum cyrtonema Hua,explore the functional components and mechanism of Polygonatum cyrtonema Hua,and clarify the research and development direction of Polygonatum cyrtonema Hua resources.Methods Through extensive literature research and analysis of the research status of Polygonatum cyrtonema Hua,a comprehensive review was conducted on the composition,content,structure,activity,and mechanism of chemical components in Polygonatum cyrtonema Hua,on the differences in the content of main chemical components such as total polysaccharides,total saponins,and total flavonoids in different origins,different growth stages,different habitats,and different parts of Polygonatum cyrtonema Hua,as well as on the extraction process of total flavonoids.Results It was found that Polygonatum cyrtonema has many biological activities,such as regulating blood sugar,anti-fatigue,enhancing immunity,anti-tumor,antibacterial,anti-virus,anticoagulant,and antidepressant effects.Its main functional components are polysaccharides,saponins,flavonoids,and alkaloids.Conclusion There are significant differences in the content of total polysaccharides,total saponins,and total flavonoids in Polygonatum cyrtonema Hua from different origins,growth stages,and habitats.The aboveground parts also contain functional components such as total polysaccharides,total saponins,and total flavonoids.In the future,it is necessary to enhance the in-depth research and development of the Polygonatum cyrtonema Hua resource,making full use of its potential.