低能量激光治疗在正畸保持中的基础研究进展

Basic Research Progress of Low Level Laser Therapy in Orthodontic Retention

正畸治疗后的复发是临床中的常见问题,如何减少复发,缩短保持期是正畸领域的研究热点。低能量激光治疗(LLLT)是一种通过光生物调节作用促进细胞增殖分化的治疗方法,与其他减少复发的方法相比,具有良好穿透性和生物安全性等特点。多数研究结果表明,在一定参数范围内,LLLT结合传统保持器可降低正畸复发率,缩短保持周期。研究认为LLLT通过影响基质金属蛋白酶(MMPs)、三磷酸腺苷(ATP)、蛋白质合成及细胞因子等,促进组织改建和修复,从而提高牙齿正畸治疗后的稳定性,其作用机制与牙周韧带(PDL)纤维重构和牙槽骨改建有关。深入研究LLLT在正畸保持中的应用,具有重要的科研及临床指导意义。就LLLT应用于正畸保持的实验研究、作用机制及关键参数的考量作一综述。

The recurrence of orthodontic issues after treatment is a common clinical concern.Addressing how to minimize recurrence and shorten the retention period is a prominent research focus in orthodontics.Low-level laser therapy(LLLT) is a treatment method that stimulates cell proliferation and differentiation through photobiomodulation,characterized by effective penetration and biosafety compared to other methods for reducing recurrence.Most research findings indicate that when combined with traditional retainers,LLLT can decrease the orthodontic recurrence rate and retention period within specific parameter ranges.Studies have suggested that LLLT influences tissue remodeling and repair by impacting Matrix metalloproteinases(MMPs),Adenosine Triphosphate(ATP),protein synthesis,cytokines,and more.It can enhance the stability of orthodontic treatment,with its mechanism linked to the remodeling of periodontal ligament(PDL) fibers and alveolar bone.Further exploration of LLLT′s application in orthodontic retention holds significant scientific research and clinical guidance implications.This paper provides a review of experimental studies,mechanisms,and key parameters of LLLT in orthodontic retention.