摘要
目前,高压氧疗法因副作用少且操作方便的特点,可作为治疗抑郁症的潜在方法。本文通过综述高压氧治疗抑郁症的临床应用现状和作用机制,以期为抑郁症治疗新策略的制定提供参考。高压氧疗法现已被作为抑郁症患者的有效疗法,可通过调节下丘脑-垂体-肾上腺轴、抑制神经炎症以及增强突触可塑性,进而改善抑郁症患者的临床症状。高压氧疗法作为抗抑郁药物的联合治疗方法,在一定程度上有助于改善治疗效果。
Hyperbaric oxygen therapy characterized by fewer side effects and simple operation has been explored as a potential therapy for depression.This article provides a review of researches relevant to current clinical application and mechanism of hyperbaric oxygen therapy for depression,aiming to provide valuable references for the formulation of new strategies for the treatment of depression.Hyperbaric oxygen therapy has been demonstrated to be useful as an adjunctive therapy for depression,which can effectively alleviate depression by regulating the homeostasis of hypothalamus-pituitary-adrenal axis,inhibiting inflammation and enhancing synaptic plasticity.And hyperbaric oxygen therapy as adjuvant to antidepressants for depression can contribute to increasing the treatment effectiveness to some extent.
作者
肖林
张小梅
吴凯
王陆
Xiao Lin;Zhang Xiaomei;Wu Kai;Wang Lu(The Fourth People's Hospital of Chengdu,Chengdu 610036,China;University of Electronic Science and Technology of China,Chengdu 611731,China;Wenjiang District People's Hospital of Chengdu,Chengdu 611130,China)
出处
《四川精神卫生》
2024年第1期91-96,共6页
Sichuan Mental Health
关键词
高压氧
抑郁症
神经炎症
突触可塑性
Hyperbaric oxygen
Depression
Neuroinflammation
Synaptic plasticity
