摘要
意识障碍(DOC)是脑损伤后常见不良结局,通常导致严重医疗与经济负担。目前DOC的发病机制尚不明确,临床诊断及预后评估缺乏可靠标志物。神经功能成像因其客观性、可重复性在探究发病机制及疾病诊治方面发挥了重要作用。本文就静息态功能磁共振成像(rs-fMRI)不同分析技术对DOC的相关研究进展作一综述,旨在为探索DOC发病机制及临床诊治提供线索。
Disorder of consciousness(DOC)is a common adverse outcome after brain injury,usually lead to severe health and economic burden.It is still unclear at present the pathogenesis of disorder of consciousness,clinical diagnosis and prognosis assessment are the lack of reliable markers.The neurological function imaging plays an important role in the probe into its pathogenesis and in disease diagnosis and treatment because of its objectivity and repeatability.In this paper,the resting-state functional MRI(rs-fMRI)of different analytical techniques associated with disorder of consciousness research progress were reviewed,aimed at exploring clues to DOC pathogenesis and clinical diagnosis and treatment.
作者
任育秦
郝宇茹
钱丽霞
REN Yuqin;HAO Yuru;QIAN Lixia(School of Medical Imaging,Shanxi Medical University,Taiyuan 030001,China;The Third Hospital of Shanxi Medical University/Shanxi Bethune Hospital/Shanxi Academy of Medical College/Tongji Shanxi Hospital,Taiyuan 030032,China)
出处
《中国实用神经疾病杂志》
2024年第3期378-382,共5页
Chinese Journal of Practical Nervous Diseases
基金
山西省基础研究计划项目(编号:202103021224344)。
关键词
意识障碍
脑网络
脑功能成像
静息态功能磁共振成像
脑损伤
Disorder of consciousness
Brain network
Functional neuroimaging
Resting-state functional magnetic resonance imaging
Brain injury