基于属性层次模型的痰热清注射液用药合理性评价

Evaluation of medication rationality of Tanreqing injection based on analytic hierarchical model

目的建立痰热清注射液的临床合理应用标准,为临床合理应用痰热清注射液提供参考依据。方法以痰热清注射液药品说明书为基础,参考《中药注射剂临床应用基本原则》、专业指南及相关文献,制定包括适应证、用法用量及溶媒选择等11个指标在内的痰热清注射液临床应用的合理性评价细则,采用属性层次模型法对本院2021年1—12月使用痰热清注射液的198例归档病历进行评价分析。结果痰热清注射液不合理应用主要问题表现为使用疗程、适应证、用法用量、联合用药等方面。在这198例病历中,病历评价得分(MRS)≥90分为24例(12.1%),80≤MRS<90分为44例(22.2%),60≤MRS<80分为82例(41.5%),MRS<60分为48例(24.2%)。结论本院痰热清注射液使用基本合理,但在使用疗程、用法用量、联合用药和适应证等方面仍有问题。基于属性层次模型的评价方法简单实用,为药物合理性应用评价提供了一种新的方法。

AIM To establish the rational clinical application standard of Tanreqing injection,providing reference for rational clinical application of Tanreqing injection.METHODS Based on the drug instructions of Tanreqing injection and referring to the Basic Principles of Clinical Application of Traditional Chinese Medicine Injections,professional guidelines and relevant literatures,the rules for evaluating the rationality of clinical application of Tanreqing injection including 11 indicators such as indications,usage and dosage,and solvent selection were formulated.The analytic hierarchical model(AHM)method was used to evaluate and analyze 198 archived medical records of Tanreqing injection from January to December 2021 in our hospital.RESULTS The main problems in the unreasonable application of Tanreqing injection included the duration of treatment,indications,usage and dosage,drug combination,etc.Among the 198 cases,24 cases(12.1%)had a medical record score(MRS)90,44 cases(22.2%)had a score of 80 MRS<90,82 cases(41.5%)had a score of 60 MRS<80,and 48 cases(24.2%)had a score of MRS<60.CONCLUSION The use of Tanreqing injection in our hospital is basically reasonable,but there are still some problems in terms of treatment course,usage and dosage,drug combination,indications,etc.The AHM method is simple and practical,which provides a new method for the evaluation of the drug rational application.