社区非酒精性脂肪肝病人群常见慢性病共病组合及变化情况分析

Analysis of the Comorbid Chronic Disease Pattern among Community Inhabitants Diagnosed with Non-alcoholic Fatty Liver Disease

目的:了解社区非酒精性脂肪肝病人群常见慢性病共病组合及变化情况,为社区人群的慢性病共病防治提供科学依据。方法:基于上海市自然人群队列松江子队列,针对社区人群于2016年和2019分别开展基线调查与随访,采用问卷调查收集人群常见慢性病患病情况,比较随访前后非酒精性脂肪肝病患者共患其他慢性病的变化情况,中位随访时间为2.96年。结果:随访前后比较,社区人群非酒精性脂肪肝病总体患病率由38.68%增长至40.78%,单纯患非酒精性脂肪肝病人群占比由34.60%提高至37.92%,共患病以高血压、糖尿病、高脂血症、甲状腺疾病、慢性胃肠炎最为常见,随访阶段发现共患高血压和糖尿病的人群占比进一步升高。结论:社区人群非酒精性脂肪肝病患病率较高,共患高血压、糖尿病、高脂血症最为常见。因此,社区非酒精性脂肪肝病人群共患其他慢性病的调查结果和慢性病管理应引起社区医疗卫生机构的重视,从而促进社区人群的健康水平。

OBJECTIVE To describe the prevalence of nonalcoholic fatty liver disease(NAFLD)among community inhabitants and elucidate the common NAFLD complication pattern.METHODS Baseline and follow-up investigation were conducted based on the Shanghai Natural Population Songjiang sub-cohort.It adopted a questionnaire to assess the prevalence of other common chronic conditions within the target population,and further compare the NAFLD patients’comorbidity pattern.RESULTS Over a median fol⁃low-up of 2.96 years,the overall NAFLD prevalence increased from 38.68%to 40.78%.The proportion of subjects with single fatty liver rose from 34.60%to 37.92%.Hypertension,diabetes,hyperlipidemia,thyroid disorder,and chronic gastroenteritis were found to be the most common comorbidity.After follow-up,the proportions of subjects with fatty liver complications of hypertension and diabetes were further increased.CONCLUSION The NAFLD prevalence was relatively high among community citizens.Hypertension,diabetes,and hyperlipidemia are the most common complications.More attention should be paid to the investigation and management of community-based NAFLD patients on the perspective of community health workers.