儿童腺病毒感染与肝脏损害的临床病例及病因探讨

Clinical and etiological analysis of adenovirus infection and liver damage in children

儿童人腺病毒感染为临床常见的,可能危及生命的疾病。自发现以来,该病毒感染遍布全球,四季均可发病。近期出现多例儿童聚集发病的不明原因重症肝炎,部分患儿因病情危重行肝移植治疗,该病的发生可能与腺病毒感染相关。文章对近10年报道的儿童腺病毒感染合并肝脏损害的病例进行分析,并探讨病因。

Human adenovirus infection in children is a common clinical disease that may be life-threatening.Since its discovery,the virus has been found all over the world and can occur in all four seasons.Recently,there have been a number of cases of unexplained severe hepatitis in children.Some of the children were treated with liver transplantation due to their critical condition.The occurrence of the disease may be related to adenovirus infection.This article summarizes the cases of adenovirus infection complicated by liver damage in children that have been reported in the last ten years,and explores their etiology.