成人肝移植患者围手术期营养管理证据总结

Evidence summary for perioperative nutrition management among adult patients with liver transplantation patients

目的:检索、评价和总结成人肝移植围手术期营养管理的相关证据,为临床制定营养策略及患者自我管理提供循证依据。方法:系统检索国内外数据库中关于成人肝移植围手术期营养管理的相关文献,根据相关文献评价标准进行评价并提取证据。结果:共纳入11篇文献,其中指南7篇、专家共识3篇、系统评价1篇,最终总结出20条证据,包括营养风险筛查与评估、骨骼肌减少症的筛查、体质量管理、术前营养管理、术后营养管理、院外随访6个方面。结论:该研究总结的成人肝移植围手术期营养管理的证据具有科学性和实用性,可为临床医护人员提供参考和借鉴,使其更有针对性、科学性地指导肝移植术后患者的自我管理。

Objective:To search,evaluate and summarize currently available state-of-the-art studies on the perioperative nutrition management of adult liver transplantation,and to provide evidence-based basis for clinical nutrition strategy development and patients'self-management.Methods:The literature on perioperative nutrition management of adult liver transplantation was systematically searched,evaluated,and extracted from the domestic and foreign databases according to the evaluation criteria.Results:A total of 11 literatures,consisting of 7 guidelines,3 expert consensus,and 1 systematic review were included.Finally,20 best evidences and 6 categories were summarized,including nutritional risk screening and assessment,sarcopenia assessment,weight management,preoperative nutrition management,postoperative nutrition management,and follow-up for discharged patients.Conclusion:Our study scientifically and practically summarizes the best evidence of perioperative nutrition management of adult liver transplantation,which provides implications for clinical medical staff and guides targeted interventions for the self-management of patients after liver transplantation.