上林县输入性间日疟和卵形疟与G6PD缺乏患者流行病学调查研究

Epidemiological investigation of imported vivax malaria,ovale malaria and G6PD deficiency patients in Shanglin County

目的统计分析上林县输入性间日疟和卵形疟与葡萄糖-6-磷酸脱氢酶(G6PD)缺乏患者流行病学特征,为疟疾防治提供科学依据。方法收集上林县人民医院2017年6月18日至2023年3月29日入院治疗输入性疟疾患者的数据进行整理分析。结果收治输入性疟疾患者共578例,其中恶性疟患者占40.48%(234/578),需要伯氨喹进行根治的间日疟、卵形疟及混合感染患者占37.54%(217/578);其中G6PD缺乏患者占10.90%(63/578),需根治的G6PD缺乏患者占9.68%(21/217)。结论上林县需要根治的输入性间日疟和卵形疟患者较多,特别是对G6PD缺乏又需根治的患者应加强管理,预防二代病例的出现。

Objective To analyze the epidemiological characteristics of imported vivax malaria,ovale malaria and glucose-6-phosphate dehydrogenase(G6PD)deficiency in Shanglin County,and to provide a scientific basis for malaria prevention and control.Methods The data of patients with imported malaria admitted to the People′s Hospital of Shanglin from June 18,2017 to March 29,2023 were collected and analyzed.Results A total of 578 patients with imported malaria were admitted,of which 40.48%(234/578)were falciparum malaria patients,and 37.54%(217/578)were vivax malaria,oval malaria and mixed infection patients who needed primaquine for radical treatment.Among them,G6PD deficiency patients accounted for 10.90%(63/578),and G6PD deficiency patients requiring radical treatment accounted for 9.68%(21/217).Conclusion There are more patients with imported vivax malaria and ovale malaria who need to be cured in Shanglin County,especially for patients with G6PD deficiency who need to be cured,management should be strengthened to prevent the occurrence of second-generation cases.