综合性干预在经导管动脉栓塞化疗的原发性肝癌患者中的应用效果

Application effect of comprehensive intervention in primary liver cancer patients undergoing transcatheter arterial chemoembolization

目的探讨综合性干预在经导管动脉栓塞化疗的原发性肝癌患者中的应用效果。方法根据干预方法的不同将104例经导管动脉栓塞化疗的原发性肝癌患者分为常规干预组和综合性干预组,每组52例。比较两组患者的胃肠功能恢复指标、院内感染情况、心理状态[焦虑自评量表(SAS)和抑郁自评量表(SDS)]、生活质量[健康调查简表(SF-36)]及并发症发生情况。结果综合性干预组患者首次排气时间、首次排便时间、肠鸣音恢复时间均明显短于常规干预组(P﹤0.01)。综合性干预组患者院内感染总发生率为3.85%,低于常规干预组患者的15.38%(P﹤0.05)。干预后,两组患者SAS、SDS评分均低于本组干预前,综合性干预组患者SAS、SDS评分均低于常规干预组,差异均有统计学意义(P﹤0.05)。干预后,两组患者SF-36各维度评分均高于本组干预前,综合性干预组患者SF-36各维度评分均高于常规干预组,差异均有统计学意义(P﹤0.05)。综合性干预组患者并发症总发生率为3.85%,明显低于常规干预组患者的26.92%(P﹤0.01)。结论综合性干预应用于经导管动脉栓塞化疗的原发性肝癌患者,可促进患者胃肠功能恢复,改善心理状态,提高生活质量,降低院内感染和并发症发生率。

Objective To explore the application effect of comprehensive intervention in primary liver cancer patients undergoing transcatheter arterial chemoembolization.Method A total of 104 primary liver cancer patients undergoing transcatheter arterial chemoembolization were divided into conventional intervention group and comprehensive intervention group,with 52 cases in each group.The gastrointestinal function recovery indexes,nosocomial infection,mental state[self-rating anxiety scale(SAS)and self-rating depression scale(SDS)],quality of life[the MOS 36-item short form health survey(SF-36)]and complications were compared between the two groups.Result The first exhaust time,first defecation time and bowel sound recovery time in the comprehensive intervention group were shorter than those in the conventional intervention group(P<0.01).The total incidence of nosocomial infection in the comprehensive intervention group was 3.85%,which was lower than 15.38%in the conventional intervention group(P<0.05).After intervention,the SAS and SDS scores of both groups were lower than those before intervention,and the SAS and SDS scores in the comprehensive intervention group were lower than those in the conventional intervention group,and the differences were statistically significant(P<0.05).After intervention,the scores of each dimension of SF-36 in both groups were higher than those before intervention,and the scores of the comprehensive intervention group were higher than those of the conventional intervention group,and the differences were statistically significant(P<0.05).The total incidence of complications in the comprehensive intervention group was 3.85%,which was lower than 26.92%in the conventional intervention group(P<0.01).Conclusion Comprehensive intervention in primary liver cancer patients undergoing transcatheter arterial chemoembolization can promote the recovery of gastrointestinal function,improve mental state and quality of life,and reduce the incidence of nosocomial infection and complications.