摘要
目的探讨MRI三维容积式插入法屏气检查(3D-VIBE)对胰腺癌的诊断价值及对可切除性的评估价值。方法选取120例胰腺癌患者,均进行自旋回波-回波平面成像(SE-EPI)与3D-VIBE序列MRI检查。以手术后的病理检查结果作为金标准,分析SE-EPI与3D-VIBE序列诊断胰腺癌T分期与术后病理T分期的一致性。采用受试者工作特征曲线(ROC)分析SE-EPI与3D-VIBE序列对胰腺癌的诊断价值。比较胰腺癌患者SE-EPI和3D-VIBE序列扫描的强化特征。以手术实际切除为标准,分析SE-EPI与3D-VIBE序列对胰腺癌可切除性的评估价值。结果SE-EPI与3D-VIBE序列诊断胰腺癌T分期与术后病理T分期的一致性均较好(Kappa=0.875、0.850,P﹤0.01)。ROC曲线显示,3D-VIBE序列诊断胰腺癌的灵敏度和曲线下面积(AUC)均高于SE-EPI序列。3D-VIBE序列的动脉早期信噪比(SNR)、动脉晚期SNR、动脉早期对比度噪声(CNR)、动脉晚期CNR均明显高于SE-EPI序列,差异均有统计学意义(P﹤0.01)。SE-EPI与3D-VIBE序列评估胰腺癌可切除性与手术实际切除的一致性均较好(Kappa=0.967、0.992,P﹤0.01)。结论MRI 3D-VIBE序列对胰腺癌及其T分期具有较高的诊断价值,且对其可切除性具有较高的评估价值。
Objective To evaluate the value of MRI three-dimensional volumetric interpolated breath-hold examination(3D-VIBE)in the diagnosis and resectability assessment of pancreatic cancer.Method A total of 120 patients with pancreatic cancer were selected and all patients were received spin echo-echo planar imaging(SE-EPI)and 3D-VIBE sequence MRI examination.Using the pathological examination results after surgery as the gold standard,the consistency of SE-EPI and 3D-VIBE sequences in diagnosis of pancreatic cancer T stage and postoperative pathological T stage were analyzed.The diagnostic value of SE-EPI and 3D-VIBE sequences in pancreatic cancer were analyzed by receiver operating characteristic(ROC)curve.The enhancement features of SE-EPI and 3D-VIBE sequences scanning in pancreatic cancer were compared.The value of SE-EPI and 3D-VIBE sequences in assessing resectability of pancreatic cancer were analyzed based on actual surgical resection.Result The results of SE-EPI and 3D-VIBE sequences for the diagnosis of pancreatic cancer T stage showed good consistency with postoperative pathological T stage(Kappa=0.875,0.850,P<0.01).ROC curve showed that the sensitivity and area under the curve(AUC)of 3D-VIBE sequence in the diagnosis of pancreatic cancer were higher than those of SE-EPI sequence.The early arterial signal-to-noise ratio(SNR),late arterial SNR,early arterial contrast-to-noise ratio(CNR)and late arterial CNR of 3D-VIBE sequence were significantly higher than those of SE-EPI sequence,and the differences were statistically significant(P<0.01).The results of SE-EPI and 3D-VIBE sequences for the resectability assessment of pancreatic cancer showed good consistency with actual surgical resection(Kappa=0.967,0.992,P<0.01).Conclusion MRI 3D-VIBE sequence has high diagnostic value for pancreatic cancer and its T stage,and has high evaluative value for its resectability.
作者
杨达
刘亚南
李倩
陈彦君
任月勤
张萍
YANG Da;LIU Ya’nan;LI Qian;CHEN Yanjun;REN Yueqin;ZHANG Ping(MRI Room,He’nan Province Hospital of Traditional Chinese Medicine(the Second Affiliated Hospital of He’nan University of Traditional Chinese Medicine),Zhengzhou 450003,He’nan,China)
出处
《癌症进展》
2024年第1期84-87,共4页
Oncology Progress
基金
河南省高等学校重点科研项目(21B320002)。
关键词
自旋回波-回波平面成像
三维容积式插入法屏气检查
胰腺癌
可切除性
spin echo-echo planar imaging
three-dimensional volumetric interpolated breath-hold examination
pancreatic cancer
resectability