精神分裂症合并代谢综合征的影响因素分析

Analysis of Influencing Factors of Schizophrenia Complicated with Metabolic Syndrome

目的:分析精神分裂症合并代谢综合征(MS)的影响因素。方法:选取2022年1月—2023年6月浙江省人民医院收治的317例精神分裂症患者作为研究对象,收集患者的临床资料,分析精神分裂症合并MS的影响因素及独立影响因素。结果:317例精神分裂症患者中合并MS 96例(30.28%),未合并MS 221例(69.72%)。年龄、病程、居住状态、内脏脂肪水平、体质量指数及蒙特利尔认知评估量表(MOCA)评分是精神分裂症患者合并MS的影响因素(P<0.05)。年龄≥40岁、病程≥5年、未婚、独居、内脏脂肪水平高、肥胖、MOCA评分<18分为精神分裂症合并MS的独立影响因素(P<0.05)。结论:临床可根据精神分裂症合并MS的相关风险因素采取针对性的干预措施以降低精神分裂症患者MS发生率。

Objective:To analyze the influencing factors of schizophrenia complicated with metabolic syndrome(MS).Methods:A total of 317 patients with schizophrenia who received treatment at Zhejiang Provincial People's Hospital from January 2022 to June 2023 were selected as the research subjects.The clinical data of patients were collected,and the influencing factors and independent influencing factors of schizophrenia complicated with MS were analyzed.Results:Among the 317 patients with schizophrenia,96 cases(30.28%) had MS and 221 cases(69.72%) had no MS.Age,course of disease,residence status,visceral fat level,body mass index,and Montreal Cognitive Assessment(MOCA) score were the influencing factors of MS in patients with schizophrenia(P<0.05).Age ≥ 40 years old,disease course ≥ 5 years,unmarried,living alone,high visceral fat level,obesity,and MOCA score < 18 points were independent influencing factors for schizophrenia complicated with MS(P<0.05).Conclusion:In clinical practice,targeted intervention measures may be adopted according to the related influencing factors of schizophrenia complicated with MS to reduce the incidence of MS in schizophrenia patients.