“改良柯药安神助眠枕”对高海拔地区睡眠障碍患者的临床疗效分析

Clinical effect of“Improved Kirgiz herbs medicated pillow”on patients with sleep disorders in high altitude area

目的分析改良柯药安神助眠枕对高海拔地区睡眠障碍患者的临床疗效。方法将60例高海拔地区睡眠障碍患者随机分为三组,治疗Ⅰ组20例患者予柯药安神枕干预,治疗Ⅱ组20例患者予改良柯药安神助眠枕干预,对照组20例患者予安慰剂干预。三组均以30 d为1个治疗干预周期,一周期后比较三组疗效,分析干预前后匹兹堡睡眠质量指数(PSQI)评分变化和疲劳自评量表(FSAS)评分变化。结果治疗Ⅰ组和治疗Ⅱ组有效率为85.0%和90.00%,均高于对照组(P<0.05);干预后三组PSQI评分比较差异有统计学意义(P<0.001)。干预后治疗Ⅰ组和治疗Ⅱ组PSQI评分均较各自干预前降低(P<0.05),治疗Ⅰ组和治疗Ⅱ组PSQI评分低于对照组,治疗Ⅱ组PSQI评分低于治疗Ⅰ组(P<0.05)。干预后三组FSAS评分比较差异有统计学意义(P<0.001)。干预后治疗Ⅰ组和治疗Ⅱ组FSAS评分均较各自干预前降低(P<0.05),治疗Ⅰ组和治疗Ⅱ组FSAS评分低于对照组,治疗Ⅱ组FSAS评分低于治疗Ⅰ组(P<0.05)。结论柯药安神枕和改良柯药安神助眠枕对治疗高海拔地区睡眠障碍均有效,但经中医理论体系对传统抗高反促安神柯药方改良研发后的改良柯药安神助眠枕效果更优,安全性良好,值得推广应用。

Objective To analyze the clinical effect of improved Kirgiz herbs medicated pillow on patients with sleep disorders in high altitude area.Methods 60 patients with sleep disorders at high altitude were randomly divided into 3 groups:20 patients in groupⅠtreated with Kirgiz herbs medicated pillow,20 patients in groupⅡtreated with improved Kirgiz herbs medicated pillow,and 20 patients in control group treated with ordinary pillow intervention.The three groups were treated for 30 days as one intervention cycle.After one period,the efficacies of the three groups were compared,and the changes of Pittsburgh Sleep Quality Index(PSQI)and Fatigue Self-Rating Scale(FSAS)scores before and after intervention were analyzed.Results The effective rates of groupⅠand groupⅡwere 85.00%and 90.00%,which were significantly higher than that of control group(P<0.05).After intervention,there existed significant differences in PSQI and FSAS scores among three groups(P<0.001).After intervention,the PSQI and FSAS scores in groupⅠand groupⅡwere significantly decreased compared with those before intervention(P<0.05),and were significantly lower than those in control group;the PSQI and FSAS scores in groupⅡwere lower than those in groupⅠ(P<0.05).Conclusion Both the Kirgiz herbs medicated pillow and the improved Kirgiz herbs medicated pillow are effective in the treatment of sleep disorders in high altitude area.But the improved Kirgiz herbs medicated pillow developed after the improvement of the traditional anti reflux and promoted Kirgiz herbs prescription through the theoretical system of traditional Chinese medicine has better effect and good safety,and is worthy of popularization and application.