精神分裂症患者社会认知与病耻感相关性研究

A study on the correlation between social cognition and stigma in patients with schizophrenia

目的:探讨精神分裂症(SCH)患者社会认知与病耻感可能的相关关系。方法:收集74例SCH患者为研究对象,并选取43名正常人为对照组,对所有受试者进行社会认知测评,对SCH患者进行病耻感测评。结果:SCH患者在人际反应指针问卷中除个人痛苦外各维度均较正常人低(P<0.05),在多伦多述情障碍量表中各维度分数均高于正常人(P<0.05),在面孔情绪识别中正确率各维度均比正常人低(P<0.05),反应时间各维度均比正常人长(P<0.05);74例SCH患者皮尔逊相关性分析提示人际反应中观点采择与贬低-歧视呈正相关、与挑战呈负相关性(P<0.05),同情关怀与误解、挑战呈负相关关系(P<0.05),个人痛苦与误解、贬低-歧视、退缩、不同/差耻各维度呈负相关关系(P<0.05),想象力与贬低-歧视呈正相关(P<0.05),难以描述、识别自己的情感与不同/羞耻呈负相关(P<0.05),外向性思维与贬低-歧视、退缩、不同/羞耻呈负相关(P<0.05),正性、中性面孔识别的正确率与不同/差耻呈正相关(P<0.05)。结论:SCH患者在社会认知各维度均受损,相关性分析结果提示社会认知与病耻感总体呈正相关关系。

Objective:To investigate the possible correlation between social cognition and stigma in patients with schizophrenia.Methods:74 SCH patients and 43 normal controls were collected.Conduct social cognitive assessment on all subjects and assess the sense of stigma in SCH patients.Result:The interpersonal response index of SCH patients was lower than that of normal people in all dimensions except personal pain(P<0.05).The scores of all dimensions of the Toronto Alexithymia Scale were higher than those of normal people(P<0.05).The correct rate of face emotion recognition in all dimensions was lower than that of normal people(P<0.05),and the reaction time of face emotion recognition was longer than that of normal people(P<0.05).Pearson correlation analysis of 74 SCH patients showed that opinion selection was positively correlated with demeaning discrimination and negatively correlated with challenge in interpersonal response(P<0.05).Compassionate care was negatively correlated with challenge and misunderstanding(P<0.05),personal pain was negatively correlated with misunderstanding,disparagediscrimination,withdrawal and difference/shame in stigma(P<0.05).Imagination was positively correlated with demeaning and discrimination(P<0.05).Difficulty in describing and recognizing one's own emotions was negatively correlated with difference/shame(P<0.05).Extroversion thinking was negatively correlated with demeaning discrimination,withdrawal,difference/shame(P<0.05).The accuracy of positive and neutral face recognition was positively correlated with dissimilarity/shame(P<0.05).Conclusion:SCH patients are impaired in all dimensions of social cognition,and the correlation analysis results suggest that social cognition is positively correlated with stigma.