早发性与晚发性结直肠癌临床特征比较及预后的分析

Comparison of clinical features and prognosis of early-and late-onset colorectal cancer

结直肠癌(colorectal cancer,CRC)是全球常见的消化系肿瘤,发病率位于世界第3,病死率位居世界第2,近年来结直肠癌总的发病率及病死率有所下降,但早发性结直肠癌(early-onset colorectal cancer,EOCRC)呈整体增长趋势.通常把<50岁诊断的结直肠癌定义为EOCRC,与晚发性结直肠癌(late-onset colorectal cancer,LOCRC)相比,其具有独特的临床特征,且预后较差.本文就EOCRC的临床特征及预后进行简要述评.

Colorectal cancer is a common digestive system tumor,ranking third in incidence and second in fatality rate in the world.In recent years,the total incidence and fatality rate of colorectal cancer decrease,but early-onset colorectal cancer(EOCRC)shows an overall rising trend.Colorectal cancer diagnosed at less than 50 years of age is generally defined as EOCRC,which has unique clinical features and a poorer prognosis than late-onset colorectal cancer.This article reviews the clinical features and prognosis of EOCRC.