肺结核患者气管支气管结核的发生率与临床预测因素分析

Analysis of incidence and clinical predictive factors of tracheobronchial tuberculosis in patients with pulmonary tuberculosis

目的 分析肺结核(PTB)患者中气管支气管结核(TBTB)的发生率以及其临床预测因素。方法 回顾性纳入梅州市人民医院2019年1—12月诊断为PTB且接受支气管镜检查患者。计算TBTB的发生率,采用logistic回归分析TBTB的临床预测因素。结果 168例患者确诊为PTB,其中有62例(36.9%)合并TBTB,病程≥4周(OR=2.573,95%CI:1.159~5.709)、女性患者(OR=2.395,95%CI:1.007~5.696)以及有咳嗽症状(OR=3.167,95%CI:1.024~9.798)是PTB患者合并TBTB的独立危险因素(P <0.05)。结论 有36.9%PTB患者合并TBTB,病程≥4周、女性、有咳嗽症状是PTB患者合并TBTB的主要临床预测因素。

Objective To analyze the incidence of tracheobronchial tuberculosis(TBTB) in patients with pulmonary tuberculosis(PTB) and its clinical predictive factors.Methods Patients who were diagnosed as PTB and underwent bronchoscopy in Meizhou People's Hospital from January to December 2019 were retrospectively included.The incidence of TBTB was calculated,and the clinical predictive factors of TBTB were analyzed by logistic regression analysis.Results In the whole year,168 patients were diagnosed as PTB,in which 62 patients(36.9%) were complicated with TBTB.Disease time ≥ 4 weeks(OR=2.573,95%CI:1.159-5.709),female gender(OR=2.395,95%CI:1.007-5.696) and cough symptom(OR=3.167,95%CI:1.024-9.798) were the independent risk factors for PTB patients complicated with TBTB(P < 0.05).Conclusion 36.9% of PTB patients are complicated with TBTB.Disease time ≥ 4 weeks,female gender and cough symptom are the main clinical predictive factors of PTB patients complicated with TBTB.